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Inhibitory constituents of the heartwood of Dalbergia odorifera on nitric oxide production in RAW 264.7 macrophages
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lee, Chul | - |
| dc.contributor.author | Lee, Jin Woo | - |
| dc.contributor.author | Jin, Qinghao | - |
| dc.contributor.author | Jang, Dae Sik | - |
| dc.contributor.author | Lee, Sung-Joon | - |
| dc.contributor.author | Lee, Dongho | - |
| dc.contributor.author | Hong, Jin Tae | - |
| dc.contributor.author | Kim, Youngsoo | - |
| dc.contributor.author | Lee, Mi Kyeong | - |
| dc.contributor.author | Hwang, Bang Yeon | - |
| dc.date.accessioned | 2021-09-05T23:48:33Z | - |
| dc.date.available | 2021-09-05T23:48:33Z | - |
| dc.date.created | 2021-06-14 | - |
| dc.date.issued | 2013-07-15 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/102709 | - |
| dc.description.abstract | Two new isoflavanones (1 and 13), along with 25 known compounds (2-12, 14-27), were isolated from the EtOAc-soluble fraction of the heartwood of Dalbergia odorifera by following their potential to inhibit the LPS-induced nitric oxide production in RAW 264.7 cells. The structures of the isolated compounds were established by spectroscopic data such as D-1, D-2 NMR and MS spectrometry. Among the isolated compounds, (2S)-pinocembrin (26), showed the most potent inhibitory effect with IC50 value of 18.1 mu M. (C) 2013 Elsevier Ltd. All rights reserved. | - |
| dc.language | English | - |
| dc.language.iso | en | - |
| dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
| dc.subject | FLAVONOIDS | - |
| dc.subject | ISOFLAVONOIDS | - |
| dc.title | Inhibitory constituents of the heartwood of Dalbergia odorifera on nitric oxide production in RAW 264.7 macrophages | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Lee, Sung-Joon | - |
| dc.contributor.affiliatedAuthor | Lee, Dongho | - |
| dc.identifier.doi | 10.1016/j.bmcl.2013.04.032 | - |
| dc.identifier.scopusid | 2-s2.0-84879416784 | - |
| dc.identifier.wosid | 000320704600051 | - |
| dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.23, no.14, pp.4263 - 4266 | - |
| dc.relation.isPartOf | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.citation.volume | 23 | - |
| dc.citation.number | 14 | - |
| dc.citation.startPage | 4263 | - |
| dc.citation.endPage | 4266 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
| dc.subject.keywordPlus | FLAVONOIDS | - |
| dc.subject.keywordPlus | ISOFLAVONOIDS | - |
| dc.subject.keywordAuthor | Dalbergia odorifera | - |
| dc.subject.keywordAuthor | Leguminosae | - |
| dc.subject.keywordAuthor | Isoflavonoid | - |
| dc.subject.keywordAuthor | Nitric oxide | - |
| dc.subject.keywordAuthor | (2S)-Pinocembrin | - |
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