Free Prostate-Specific Antigen Provides More Precise Data on Benign Prostate Volume Than Total Prostate-Specific Antigen in Korean Population
DC Field | Value | Language |
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dc.contributor.author | Choi, Hoon | - |
dc.contributor.author | Park, Jae Young | - |
dc.contributor.author | Shim, Ji Sung | - |
dc.contributor.author | Kim, Jae Heon | - |
dc.contributor.author | Bae, Jae Hyun | - |
dc.date.accessioned | 2021-09-06T00:45:52Z | - |
dc.date.available | 2021-09-06T00:45:52Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2013-06 | - |
dc.identifier.issn | 2093-4777 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/103005 | - |
dc.description.abstract | Purpose: To investigate the efficacy of total prostate-specific antigen (tPSA) and free prostate-specific antigen (fPSA) for the estimation of prostate volume (PV) in pathologically-proven benign prostatic hyperplasia (BPH) patients. Methods: From January 2010 to March 2013, 165 Korean men with a PSA less than 10 ng/mL who were diagnosed without prostate cancer by prostate biopsy were enrolled. Patients were classified into three age groups: <= 60, 61-70, and >70 years old. The results were organized to estimate and compare the ability of serum tPSA and fPSA to assess the PV. Results: Enrolled patients had a median age of 63.5 years (44 to 80), a median tPSA of 5.72 ng/mL, a median fPSA of 0.98 ng/mL and a median PV of 53.68 mL, respectively. Among the associations between tPSA, fPSA, age, and PV, the highest correlation was verified between fPSA and PV (r = 0.377, P < 0.0001); the correlation coefficient between tPSA and PV was much lower (r = 0.262, P < 0.001). All stratified age cohorts showed the same findings. The ROC curves (for PV greater than 30, 40, and 50 mL) showed that fPSA (area under the curve [AUC] = 0.781, 0.718, and 0.700) outperformed tPSA (AUC = 0.657, 0.583, and 0.67) in its ability to predict clinically significant PV enlargement. Conclusion: Both tPSA and fPSA significantly correlated with PV in Korean men, while the correlation efficiency between fPSA and PV was more powerful. fPSA may be a useful tool in making therapeutic decisions and follow-up management in BPH patients. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN CONTINENCE SOC | - |
dc.subject | ACUTE URINARY RETENTION | - |
dc.subject | TOTAL PSA | - |
dc.subject | SERUM | - |
dc.subject | HYPERPLASIA | - |
dc.subject | PREDICTOR | - |
dc.subject | MEN | - |
dc.subject | CANCER | - |
dc.subject | ALPHA-1-ANTICHYMOTRYPSIN | - |
dc.subject | FINASTERIDE | - |
dc.subject | THERAPY | - |
dc.title | Free Prostate-Specific Antigen Provides More Precise Data on Benign Prostate Volume Than Total Prostate-Specific Antigen in Korean Population | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Hoon | - |
dc.contributor.affiliatedAuthor | Park, Jae Young | - |
dc.contributor.affiliatedAuthor | Bae, Jae Hyun | - |
dc.identifier.doi | 10.5213/inj.2013.17.2.73 | - |
dc.identifier.scopusid | 2-s2.0-84880805658 | - |
dc.identifier.wosid | 000339572700006 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL NEUROUROLOGY JOURNAL, v.17, no.2, pp.73 - 77 | - |
dc.relation.isPartOf | INTERNATIONAL NEUROUROLOGY JOURNAL | - |
dc.citation.title | INTERNATIONAL NEUROUROLOGY JOURNAL | - |
dc.citation.volume | 17 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 73 | - |
dc.citation.endPage | 77 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001785542 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Urology & Nephrology | - |
dc.relation.journalWebOfScienceCategory | Urology & Nephrology | - |
dc.subject.keywordPlus | ACUTE URINARY RETENTION | - |
dc.subject.keywordPlus | TOTAL PSA | - |
dc.subject.keywordPlus | SERUM | - |
dc.subject.keywordPlus | HYPERPLASIA | - |
dc.subject.keywordPlus | PREDICTOR | - |
dc.subject.keywordPlus | MEN | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | ALPHA-1-ANTICHYMOTRYPSIN | - |
dc.subject.keywordPlus | FINASTERIDE | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordAuthor | Prostate-specific antigen | - |
dc.subject.keywordAuthor | Prostatic hyperplasia | - |
dc.subject.keywordAuthor | Organ volume | - |
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