The effect of anodized implants coated with combined rhBMP-2 and recombinant human vascular endothelial growth factors on vertical bone regeneration in the marginal portion of the peri-implant
DC Field | Value | Language |
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dc.contributor.author | Kim, Jong-Eun | - |
dc.contributor.author | Kang, Seong-Su | - |
dc.contributor.author | Choi, Kyung-Hee | - |
dc.contributor.author | Shim, June-Sung | - |
dc.contributor.author | Jeong, Chang-Mo | - |
dc.contributor.author | Shin, Sang-Wan | - |
dc.contributor.author | Huh, Jung-Bo | - |
dc.date.accessioned | 2021-09-06T00:52:37Z | - |
dc.date.available | 2021-09-06T00:52:37Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2013-06 | - |
dc.identifier.issn | 2212-4403 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/103017 | - |
dc.description.abstract | Objectives. The aim of this study was to evaluate the effect of anodized implants coated with combined rhBMP-2 and recombinant human vascular endothelial growth factors (rhVEGFs) on vertical bone regeneration in the marginal portion of the peri-implant. Study Design. Supra-alveolar defects were created in 3 male beagle dogs. Each animal received 8 implants that were either coated with a single growth factor (rhBMP-2) or combined growth factors (rhBMP-2 + rhVEGF), or an anodized implant (the control group). The amount of the vertical bone regeneration, the bone-implant contact, and the intrathread bone density were investigated using histomorphometric analysis at 8 weeks. Results. The bone morphogenetic protein (BMP) group and the BMP-VEGF group showed vertical alveolar bone regeneration and enhanced bone-implant contact in the microthread compared with the control group (P < .05). Conclusions. Anodized implants coated with rhBMP-2 and rhBMP - 2 + rhVEGF can induce vertical alveolar bone regeneration, but the combined effect of rhBMP-2 and rhVEGF was not verified. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | SIZE DEFECT MODEL | - |
dc.subject | MORPHOGENETIC PROTEIN-2 | - |
dc.subject | TITANIUM IMPLANTS | - |
dc.subject | DENTAL IMPLANT | - |
dc.subject | FACTOR VEGF | - |
dc.subject | OSTEOBLAST DIFFERENTIATION | - |
dc.subject | DUAL DELIVERY | - |
dc.subject | OSSEOINTEGRATION | - |
dc.subject | AUGMENTATION | - |
dc.subject | ANGIOGENESIS | - |
dc.title | The effect of anodized implants coated with combined rhBMP-2 and recombinant human vascular endothelial growth factors on vertical bone regeneration in the marginal portion of the peri-implant | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Sang-Wan | - |
dc.identifier.doi | 10.1016/j.oooo.2011.10.040 | - |
dc.identifier.scopusid | 2-s2.0-84878294646 | - |
dc.identifier.wosid | 000320368600004 | - |
dc.identifier.bibliographicCitation | ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, v.115, no.6, pp.E24 - E31 | - |
dc.relation.isPartOf | ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY | - |
dc.citation.title | ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY | - |
dc.citation.volume | 115 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | E24 | - |
dc.citation.endPage | E31 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Dentistry, Oral Surgery & Medicine | - |
dc.relation.journalWebOfScienceCategory | Dentistry, Oral Surgery & Medicine | - |
dc.subject.keywordPlus | SIZE DEFECT MODEL | - |
dc.subject.keywordPlus | MORPHOGENETIC PROTEIN-2 | - |
dc.subject.keywordPlus | TITANIUM IMPLANTS | - |
dc.subject.keywordPlus | DENTAL IMPLANT | - |
dc.subject.keywordPlus | FACTOR VEGF | - |
dc.subject.keywordPlus | OSTEOBLAST DIFFERENTIATION | - |
dc.subject.keywordPlus | DUAL DELIVERY | - |
dc.subject.keywordPlus | OSSEOINTEGRATION | - |
dc.subject.keywordPlus | AUGMENTATION | - |
dc.subject.keywordPlus | ANGIOGENESIS | - |
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