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Enhancement of Supercritical CO2 Inactivation of Spores of Penicillium oxalicum by Ethanol Cosolvent

Authors
Park, Hyong SeokKim, Kyoung Heon
Issue Date
6월-2013
Publisher
KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY
Keywords
Supercritical carbon dioxide; inactivation; fungal spores; Penicillium oxalicum; cosolvent; ethanol
Citation
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.23, no.6, pp.833 - 836
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
Volume
23
Number
6
Start Page
833
End Page
836
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/103029
DOI
10.4014/jmb.1211.11072
ISSN
1017-7825
Abstract
The inactivation of spores of Penicillium oxalicum by supercritical carbon dioxide (SC-CO2) was optimized by response surface methodology. The optimal inactivation conditions of 16.8 MPa, 49 degrees C, and 20 min were determined using ridge analysis, at which the predicted and experimental log(10) reductions were obtained as 5.74 and 6.12, respectively. The synergistic effect of a cosolvent (ethanol), which was used to modify SC-CO2, on the inactivation of the fungal spores was investigated. At less severe conditions of 10 MPa and 40 degrees C, I oxalicum spores of 10(7) CFU/ml were completely inactivated within 45 min by SC-CO2 modified with ethanol.
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