A Comparative Pilot Study of Symptom Improvement Before and After Phototherapy in Korean Patients with Perennial Allergic Rhinitis
DC Field | Value | Language |
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dc.contributor.author | Lee, Heung-Man | - |
dc.contributor.author | Park, Man Sik | - |
dc.contributor.author | Park, Il Ho | - |
dc.contributor.author | Lee, Seung Hoon | - |
dc.contributor.author | Lee, Seong Keon | - |
dc.contributor.author | Kim, Kyu-Sung | - |
dc.contributor.author | Choi, Hyuk | - |
dc.date.accessioned | 2021-09-06T02:17:25Z | - |
dc.date.available | 2021-09-06T02:17:25Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-05 | - |
dc.identifier.issn | 0031-8655 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/103452 | - |
dc.description.abstract | Although allergic rhinitis is not life threatening, it significantly influences the quality of a patient's life. This study is intended to evaluate the safety and efficacy of phototherapy with low-level energy of a 650nm laser irradiation system in perennial allergic rhinitis patients. This clinical trial was an open-label, single-center study with 42 perennial allergic rhinitis subjects. Following laser irradiation in the nasal cavity with a laser irradiation system, the efficacy at weeks 1 through 4 was determined. The symptoms were scored with four parameters (nasal obstruction, rhinorrhea, sneezing and itching) before and after illumination of the laser, and the total score was recorded. A survey of Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) was conducted by patients before and after treatment. Following treatment, significant improvement in the clinical symptoms of nasal obstruction (P<0.001), rhinorrhea (P=0.005), sneezing (P=0.001) and itching (P=0.003) was reported by 68% of perennial allergic rhinitis patients. The overall RQLQ scores significantly improved by 45% from the baseline with the treatment after 4weeks. These results indicate that phototherapy is an effective modality for treating perennial allergic rhinitis and is another option in the steroid-free management of immune-mediated mucosal diseases. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject | CHLORIDE ULTRAVIOLET-B | - |
dc.subject | SUBLINGUAL IMMUNOTHERAPY | - |
dc.subject | INTRANASAL PHOTOTHERAPY | - |
dc.subject | LASER | - |
dc.subject | IRRADIATION | - |
dc.subject | PROLIFERATION | - |
dc.subject | ASTHMA | - |
dc.subject | DAMAGE | - |
dc.subject | IGE | - |
dc.title | A Comparative Pilot Study of Symptom Improvement Before and After Phototherapy in Korean Patients with Perennial Allergic Rhinitis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Heung-Man | - |
dc.contributor.affiliatedAuthor | Park, Il Ho | - |
dc.contributor.affiliatedAuthor | Lee, Seung Hoon | - |
dc.contributor.affiliatedAuthor | Choi, Hyuk | - |
dc.identifier.doi | 10.1111/php.12032 | - |
dc.identifier.scopusid | 2-s2.0-84876808838 | - |
dc.identifier.wosid | 000318232800029 | - |
dc.identifier.bibliographicCitation | PHOTOCHEMISTRY AND PHOTOBIOLOGY, v.89, no.3, pp.751 - 757 | - |
dc.relation.isPartOf | PHOTOCHEMISTRY AND PHOTOBIOLOGY | - |
dc.citation.title | PHOTOCHEMISTRY AND PHOTOBIOLOGY | - |
dc.citation.volume | 89 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 751 | - |
dc.citation.endPage | 757 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.subject.keywordPlus | CHLORIDE ULTRAVIOLET-B | - |
dc.subject.keywordPlus | SUBLINGUAL IMMUNOTHERAPY | - |
dc.subject.keywordPlus | INTRANASAL PHOTOTHERAPY | - |
dc.subject.keywordPlus | LASER | - |
dc.subject.keywordPlus | IRRADIATION | - |
dc.subject.keywordPlus | PROLIFERATION | - |
dc.subject.keywordPlus | ASTHMA | - |
dc.subject.keywordPlus | DAMAGE | - |
dc.subject.keywordPlus | IGE | - |
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