Sol-gel derived nanoscale bioactive glass (NBG) particles reinforced poly(epsilon-caprolactone) composites for bone tissue engineering
DC Field | Value | Language |
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dc.contributor.author | Lei, Bo | - |
dc.contributor.author | Shin, Kwan-Ha | - |
dc.contributor.author | Noh, Da-Young | - |
dc.contributor.author | Jo, In-Hwan | - |
dc.contributor.author | Koh, Young-Hag | - |
dc.contributor.author | Kim, Hyoun-Ee | - |
dc.contributor.author | Kim, Sung Eun | - |
dc.date.accessioned | 2021-09-06T02:42:38Z | - |
dc.date.available | 2021-09-06T02:42:38Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-04-01 | - |
dc.identifier.issn | 0928-4931 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/103526 | - |
dc.description.abstract | This study investigated the effect of the addition of sal-gel derived nanoscale bioactive glass (NBG) particles on the mechanical properties and biological performances of PCL polymer, in order to evaluate the potential applications of PCL/NBG composites for bone tissue regeneration. Regardless of the NBG contents (10, 20, and 30 wt.%), the NBG particles, which were synthesized through the sol-gel process using polyethylene glycol (PEG) polymer as a template, could be uniformly dispersed in the PCL matrix, while generating pores in the PCL/NBG composites. The elastic modulus of the PCL/NBG composites increased remarkably from 89 +/- 11 MPa to 383 +/- 50 MPa with increasing NBG content from 0 to 30 wt.%, while still showing good ultimate tensile strength in the range of 15-19 MPa. The hydrophilicity, water absorption and degradation behavior of the PCL/NBG composites were also enhanced by the addition of the NBG particles. Furthermore, the PCL/NBG composite with a NBG content of 30 wt.% showed significantly enhanced in vitro bioactivity and cellular response compared to those of the pure PCL. (C) 2012 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.subject | MECHANICAL-PROPERTIES | - |
dc.subject | IN-VITRO | - |
dc.subject | NANOCOMPOSITES | - |
dc.subject | MICROSPHERES | - |
dc.subject | DEGRADATION | - |
dc.subject | FABRICATION | - |
dc.subject | SCAFFOLDS | - |
dc.subject | POLYMER | - |
dc.title | Sol-gel derived nanoscale bioactive glass (NBG) particles reinforced poly(epsilon-caprolactone) composites for bone tissue engineering | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Koh, Young-Hag | - |
dc.identifier.doi | 10.1016/j.msec.2012.11.039 | - |
dc.identifier.scopusid | 2-s2.0-84873414201 | - |
dc.identifier.wosid | 000315751600013 | - |
dc.identifier.bibliographicCitation | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, v.33, no.3, pp.1102 - 1108 | - |
dc.relation.isPartOf | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | - |
dc.citation.title | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | - |
dc.citation.volume | 33 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 1102 | - |
dc.citation.endPage | 1108 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.subject.keywordPlus | MECHANICAL-PROPERTIES | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | NANOCOMPOSITES | - |
dc.subject.keywordPlus | MICROSPHERES | - |
dc.subject.keywordPlus | DEGRADATION | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | SCAFFOLDS | - |
dc.subject.keywordPlus | POLYMER | - |
dc.subject.keywordAuthor | Bioactive glass | - |
dc.subject.keywordAuthor | Biodegradation | - |
dc.subject.keywordAuthor | Polymer | - |
dc.subject.keywordAuthor | Composite | - |
dc.subject.keywordAuthor | Hard tissue | - |
dc.subject.keywordAuthor | Mechanical properties | - |
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