Inhibitory effect of chaga mushroom extract on compound 48/80-induced anaphylactic shock and IgE production in mice
DC Field | Value | Language |
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dc.contributor.author | Yoon, Taek Joon | - |
dc.contributor.author | Lee, Sue Jung | - |
dc.contributor.author | Kim, Eun Young | - |
dc.contributor.author | Cho, Eun Hee | - |
dc.contributor.author | Kang, Tae Bong | - |
dc.contributor.author | Yu, Kwang-Won | - |
dc.contributor.author | Suh, Hyung Joo | - |
dc.date.accessioned | 2021-09-06T03:10:45Z | - |
dc.date.available | 2021-09-06T03:10:45Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-04 | - |
dc.identifier.issn | 1567-5769 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/103664 | - |
dc.description.abstract | Chaga mushrooms (Inonotus obliquus) are hypothesised to exhibit general immune-potentiating, anti-inflammatory, and antitumor properties, but their anti-allergic activities are not fully understood. Therefore, this study investigated whether a chaga mushroom extract (C-HE) might have anti-allergic activity. This activity was assessed through the levels of the IgE Ab produced in response to an allergen (OVA). The administration of C-HE prophylactically inhibited the systemic anaphylactic shock induced by compound 48/80 in mice. The oral administration of C-HE significantly reduced the total IgE levels in mice and slightly affected the production of IgG1. Furthermore, spleen cell cultures harvested from OVA-sensitised mice that had received C-HE orally showed a significant increase in Th1-derived responses (IFN-gamma production). Therefore, our results suggest that the chaga mushroom extract may be used as an anti-allergic functional food. (c) 2013 Published by Elsevier B.V. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.subject | OVALBUMIN | - |
dc.subject | INDUCTION | - |
dc.subject | RESPONSES | - |
dc.title | Inhibitory effect of chaga mushroom extract on compound 48/80-induced anaphylactic shock and IgE production in mice | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Suh, Hyung Joo | - |
dc.identifier.doi | 10.1016/j.intimp.2013.03.015 | - |
dc.identifier.scopusid | 2-s2.0-84875938036 | - |
dc.identifier.wosid | 000318392800003 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL IMMUNOPHARMACOLOGY, v.15, no.4, pp.666 - 670 | - |
dc.relation.isPartOf | INTERNATIONAL IMMUNOPHARMACOLOGY | - |
dc.citation.title | INTERNATIONAL IMMUNOPHARMACOLOGY | - |
dc.citation.volume | 15 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 666 | - |
dc.citation.endPage | 670 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | OVALBUMIN | - |
dc.subject.keywordPlus | INDUCTION | - |
dc.subject.keywordPlus | RESPONSES | - |
dc.subject.keywordAuthor | Inonotus obliquus | - |
dc.subject.keywordAuthor | Allergy | - |
dc.subject.keywordAuthor | Anaphylaxis | - |
dc.subject.keywordAuthor | Ovalbumin | - |
dc.subject.keywordAuthor | IgE | - |
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