Thermal stability of yeast hydrolysate as a novel anti-obesity material
- Authors
- Park, Yooheon; Kim, Jae Hwan; Lee, Hyun-Sun; Jung, Eun Young; Lee, Hyunji; Noh, Dong Ouk; Suh, Hyung Joo
- Issue Date
- 15-1월-2013
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Yeast hydrolysate; Thermal stability; CART; NPY
- Citation
- FOOD CHEMISTRY, v.136, no.2, pp.316 - 321
- Indexed
- SCIE
SCOPUS
- Journal Title
- FOOD CHEMISTRY
- Volume
- 136
- Number
- 2
- Start Page
- 316
- End Page
- 321
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/104191
- DOI
- 10.1016/j.foodchem.2012.08.047
- ISSN
- 0308-8146
- Abstract
- We examined the thermal stability of yeast hydrolysates before and after ultrafiltration (UF) in vitro, and the anti-obesity activity of yeast hydrolysates before and after heat treatment in vivo. Yeast hydrolysate after UF showed significantly higher thermal stability than before UF. Yeast hydrolysates before and after UF showed 3 and 4 thermal transition peaks in their thermograms, respectively, and the total thermal denaturation enthalpies of yeast hydrolysates before and after UF were 69.5 and 36.5 J/g, respectively. For the anti-obesity activity study, yeast hydrolysates before and after heating were administered ad libitum with water to 7-week-old male SD rats. The administration of yeast hydrolysate (YH-control; no heat treatment, YH-1; heat treatment at 140 degrees C, and YH-2; heat treatment at 160 degrees C) significantly increased mRNA expression of cocaine- and amphetamine-regulated transcript (CART) compared with control rats (saline administration). However, there was no significant difference between the heat-treated groups and YH-control and there was no significant difference in neuropeptide Y expression between the heat-treated groups and YH-control. These results suggest that yeast hydrolysate can be use an anti-obesity material after heat treatment. (C) 2012 Elsevier Ltd. All rights reserved.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Health Sciences > School of Biosystems and Biomedical Sciences > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.