Hepatitis A virus infection during pregnancy in Korea: Hepatitis A infection on pregnant womenHepatitis A virus infection during pregnancy in Korea: Hepatitis A infection on pregnant women
- Other Titles
- Hepatitis A virus infection during pregnancy in Korea: Hepatitis A infection on pregnant women
- Authors
- 조금준; 김윤병; 김성민; 홍혜리; 김지훈; 설현주; 홍순철; 오민정; 김해중
- Issue Date
- 2013
- Publisher
- 대한산부인과학회
- Keywords
- Hepatitis A; Pregnancy; Pregnancy complications
- Citation
- Obstetrics & Gynecology Science, v.56, no.06, pp.368 - 374
- Indexed
- KCI
- Journal Title
- Obstetrics & Gynecology Science
- Volume
- 56
- Number
- 06
- Start Page
- 368
- End Page
- 374
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/104431
- DOI
- 10.5468/ogs.2013.56.6.368
- ISSN
- 2287-8580
- Abstract
- Objective
Although there is a large body of data on acute hepatitis A virus (HAV) worldwide, data regarding the occurrence of HAV during pregnancy is limited. It is commonly acknowledged that HAV is not associated with severe outcomes or complications during pregnancy. In contrast, there are several reported cases of vertical HAV transmission. Moreover, it has been recently reported that HAV infection during pregnancy is associated with gestational complications. In Korea, the incidence of HAV infection has increased from 317 cases in 2002 to 13,117 cases in 2009. However, HAV infection during pregnancy is rarely reported in Korea.
Methods
This study was conducted as a retrospective cohort series of pregnant women presenting to Korea University Medical Center between January 2000 and October 2009 in whom a diagnosis of HAV infection was made.
Results
During study period, there were 12 cases of HAV in pregnant women, including two cases with preterm contraction, two cases with cholestatic hepatitis, and one case with fetal ascites and intra-abdominal calcification.
Conclusion
HAV infection during pregnancy is associated with high prevalence of maternal and fetal complications. Because the incidence of HAV infection in women of reproductive age is increasing, a further focus on preventing HAV infection during pregnancy is warranted.
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