Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Enterovirus 71-related encephalomyelitis: usual and unusual magnetic resonance imaging findings

Authors
Jang, SeonahSuh, Sang-ilHa, Su MinByeon, Jung HyeEun, Baik-LinLee, Young HenSeo, Hyung SukEun, So-HeeSeol, Hae-Young
Issue Date
3월-2012
Publisher
SPRINGER
Keywords
Enterovirus 71; Encephalitis; Magnetic resonance
Citation
NEURORADIOLOGY, v.54, no.3, pp.239 - 245
Indexed
SCIE
SCOPUS
Journal Title
NEURORADIOLOGY
Volume
54
Number
3
Start Page
239
End Page
245
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/105359
DOI
10.1007/s00234-011-0921-8
ISSN
0028-3940
Abstract
Most enterovirus (EV) 71 infections manifest as mild cases of hand-foot-mouth disease (HFMD)/herpangina with seasonal variations, having peak incidence during the summer. Meanwhile, EV 71 may involve the central nervous system (CNS), causing severe neurologic disease. In many cases, enteroviral encephalomyelitis involves the central midbrain, posterior portion of the medulla oblongata and pons, bilateral dentate nuclei of the cerebellum, and the ventral roots of the cervical spinal cord, and the lesions show hyperintensity on T2-weighted and fluid-attenuation inversion recovery (FLAIR) images. Our goal was to review usual and unusual magnetic resonance (MR) findings in CNS involvement of enteroviral infection. Among consecutive patients who had HFMD and clinically suspected encephalitis or myelitis and who underwent brain or spinal MR imaging, five patients revealed abnormal MR findings. Diffusion-weighted and conventional MR and follow-up MR images were obtained. From cerebrospinal fluid, stool, or nasopharyngeal swabs, EV 71 was confirmed in all patients. MR imaging studies of two patients showed hyperintensity in the posterior portion of the brainstem on T2-weighted and FLAIR images, which is the well-known MR finding of EV 71 encephalitis. The remaining three cases revealed unusual manifestations: leptomeningeal enhancement, abnormal enhancement along the ventral roots at the conus medullaris level without brain involvement, and hyperintensity in the left hippocampus on T2/FLAIR images. EV 71 encephalomyelitis shows relatively characteristic MR findings; therefore, imaging can be helpful in radiologic diagnosis. However, physicians should also be aware of unusual radiologic manifestations of EV 71.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Medical Science > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Lee, Young Hen photo

Lee, Young Hen
의과대학 (의학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE