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Eight weeks of conjugated linoleic acid supplementation has no effect on antioxidant status in healthy overweight/obese Korean individuals

Authors
Kim, JungmiPaik, Hyun-DongShin, Min-JeongPark, Eunju
Issue Date
Mar-2012
Publisher
SPRINGER HEIDELBERG
Keywords
Conjugated linoleic acid; Overweight/obese; Antioxidant status
Citation
EUROPEAN JOURNAL OF NUTRITION, v.51, no.2, pp.135 - 141
Indexed
SCIE
SCOPUS
Journal Title
EUROPEAN JOURNAL OF NUTRITION
Volume
51
Number
2
Start Page
135
End Page
141
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/105416
DOI
10.1007/s00394-011-0199-y
ISSN
1436-6207
Abstract
The aim of this study was to evaluate the effect of CLA supplementation on antioxidant metabolism in healthy overweight/obese Korean individuals. We performed a randomized, double-blind, placebo-controlled trial, where 29 healthy overweight/obese (BMI a parts per thousand yen 23 kg/m(2)) participants (2 men and 27 women) were randomly selected to receive placebo (n = 15, 2.4 g olive oil/day) or 2.4 g/day CLA mixture (n = 14, 36.9% of cis-9, trans-11 and 37.9% of trans-10, cis-12) for 8 weeks. There were no significant differences in plasma total radical-trapping antioxidant potential (TRAP), lipid peroxidation (conjugated dienes), lipid-soluble antioxidant vitamin concentration, erythrocyte antioxidant enzyme (superoxide dismutase, catalase, glutathione peroxidase) activities, and leukocyte DNA damage between the CLA and placebo groups. The data suggest that short-term supplementation (8 weeks) with CLA (2.4 g/day) might have no significant effects on lipid peroxidation and antioxidant metabolism.
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