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Recent advances in idiopathic pulmonary fibrosis

Authors
Park, S.Lee, E.J.
Issue Date
2013
Keywords
Clinical trial; Etiology; Idiopathic pulmonary fibrosis
Citation
Tuberculosis and Respiratory Diseases, v.74, no.1, pp.1 - 6
Indexed
SCOPUS
KCI
Journal Title
Tuberculosis and Respiratory Diseases
Volume
74
Number
1
Start Page
1
End Page
6
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/105872
DOI
10.4046/trd.2013.74.1.1
ISSN
1738-3536
Abstract
The concept on idiopathic pulmonary fibrosis (IPF) pathogenesis has progressed from chronic inflammation to aberrant wounding healing and even more to the current paradigms of a multifactorial and heterogeneous disease process. Despite the growth of clinical trials for IPF, most of the results, including N-acetylcysteine combination, warfarin, and bosentan, were disappointing. On the other hand, there have been a number of important developments; the foremost is the licensing of pirfenidone in Europe and Asia. In this article, we briefly review the recent knowledge of pathogenesis of IPF. We also summarize the recent clinical trials regarding the management of IPF. Copyright©2013. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.
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