ScholarWorks@Korea University

Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Cd2+ binds to Atx1 and affects the physical interaction between Atx1 and Ccc2 in Saccharomyces cerevisiae

Full metadata record
DC Field Value Language
dc.contributor.authorHeo, Dong-Hyuk-
dc.contributor.authorBaek, In-Joon-
dc.contributor.authorKang, Hyun-Jun-
dc.contributor.authorKim, Ji-Hyun-
dc.contributor.authorChang, Miwha-
dc.contributor.authorKang, Chang-Min-
dc.contributor.authorYun, Cheol-Won-
dc.date.accessioned2021-09-06T10:28:09Z-
dc.date.available2021-09-06T10:28:09Z-
dc.date.created2021-06-19-
dc.date.issued2012-02-
dc.identifier.issn0141-5492-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/106129-
dc.description.abstractThe ATX1 deletion strain of Saccharomyces cerevisiae is more resistant to Cd2+ than the wild-type. To investigate the function of Atx1 in Cd2+ toxicity, we used a metal-binding assay to study the interaction between Atx1 and Cd2+ in vitro. Using circular dichroism and two-hybrid analyses, we found that Atx1 can bind Cd2+ specifically and that Cd2+ binding to Atx1 affects the physical interaction between Atx1 and Ccc2. These results imply that Atx1 delivers Cd2+ to Ccc2 and that this delivery is, at least in part, responsible for Cd2+ toxicity in S. cerevisiae.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherSPRINGER-
dc.subjectCOPPER TRANSPORT-
dc.subjectOXYGEN-TOXICITY-
dc.subjectIRON TRANSPORT-
dc.subjectCADMIUM-
dc.subjectGENE-
dc.subjectPROTEIN-
dc.subjectHOMEOSTASIS-
dc.subjectCHAPERONE-
dc.titleCd2+ binds to Atx1 and affects the physical interaction between Atx1 and Ccc2 in Saccharomyces cerevisiae-
dc.typeArticle-
dc.contributor.affiliatedAuthorYun, Cheol-Won-
dc.identifier.doi10.1007/s10529-011-0763-9-
dc.identifier.scopusid2-s2.0-84856232507-
dc.identifier.wosid000299510200017-
dc.identifier.bibliographicCitationBIOTECHNOLOGY LETTERS, v.34, no.2, pp.303 - 307-
dc.relation.isPartOfBIOTECHNOLOGY LETTERS-
dc.citation.titleBIOTECHNOLOGY LETTERS-
dc.citation.volume34-
dc.citation.number2-
dc.citation.startPage303-
dc.citation.endPage307-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiotechnology & Applied Microbiology-
dc.relation.journalWebOfScienceCategoryBiotechnology & Applied Microbiology-
dc.subject.keywordPlusCOPPER TRANSPORT-
dc.subject.keywordPlusOXYGEN-TOXICITY-
dc.subject.keywordPlusIRON TRANSPORT-
dc.subject.keywordPlusCADMIUM-
dc.subject.keywordPlusGENE-
dc.subject.keywordPlusPROTEIN-
dc.subject.keywordPlusHOMEOSTASIS-
dc.subject.keywordPlusCHAPERONE-
dc.subject.keywordAuthorAtx1-
dc.subject.keywordAuthorCadmium-
dc.subject.keywordAuthorCcc2-
dc.subject.keywordAuthorCopper-
dc.subject.keywordAuthorSaccharomyces cerevisiae-
Files in This Item
There are no files associated with this item.
Appears in
Collections
Graduate School > Department of Life Sciences > 1. Journal Articles
Show simple item record

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Yun, Cheol Won photo

Yun, Cheol Won
생명과학대학 (생명과학부)
Read more

Altmetrics

Total Views & Downloads

STATISTICS
Total View :8,730,657
Today View :13,571

RSS_1.0 RSS_2.0 ATOM_1.0

CONTACT US

(02841) 서울특별시 성북구 안암로 14502-3290-1114

COPYRIGHT © 2021 Korea University. All Rights Reserved.

Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.

BROWSE

English