Anti-glycation Effect of Gold Nanoparticles on Collagen
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Ji-hoon | - |
dc.contributor.author | Hong, Chung-Oui | - |
dc.contributor.author | Koo, Yun-chang | - |
dc.contributor.author | Choi, Hee-Don | - |
dc.contributor.author | Lee, Kwang-Won | - |
dc.date.accessioned | 2021-09-06T10:42:17Z | - |
dc.date.available | 2021-09-06T10:42:17Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2012-02 | - |
dc.identifier.issn | 0918-6158 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/106211 | - |
dc.description.abstract | Gold nanoparticles (GNPs) have been reported to exhibit a variety of biological effects including antiinflammatory and anti-oxidant activities. The extent of an in vitro glycation reaction mixture of collagen and glycolaldehyde was assayed to investigate the inhibition of glycolaldehye-derived advanced glycation end products (glycol-AGEs) formation with GNPs in collagen, which is a major protein component of the human dermis. GNP-treated collagen showed significantly less glycation (56.3 +/- 4.2%) than an untreated glycation control. Moreover, GNP-treated glycation in a collagen lattice model significantly decreased the AGEs distribution in the model system. Taken together, these results suggest that GNPs have the potential for use in the prevention of glycation-induced skin aging. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PHARMACEUTICAL SOC JAPAN | - |
dc.subject | END-PRODUCTS | - |
dc.subject | RECONSTRUCTED SKIN | - |
dc.subject | MAILLARD REACTION | - |
dc.subject | SIZE | - |
dc.title | Anti-glycation Effect of Gold Nanoparticles on Collagen | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Kwang-Won | - |
dc.identifier.doi | 10.1248/bpb.35.260 | - |
dc.identifier.scopusid | 2-s2.0-84863078915 | - |
dc.identifier.wosid | 000299494800019 | - |
dc.identifier.bibliographicCitation | BIOLOGICAL & PHARMACEUTICAL BULLETIN, v.35, no.2, pp.260 - 264 | - |
dc.relation.isPartOf | BIOLOGICAL & PHARMACEUTICAL BULLETIN | - |
dc.citation.title | BIOLOGICAL & PHARMACEUTICAL BULLETIN | - |
dc.citation.volume | 35 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 260 | - |
dc.citation.endPage | 264 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | END-PRODUCTS | - |
dc.subject.keywordPlus | RECONSTRUCTED SKIN | - |
dc.subject.keywordPlus | MAILLARD REACTION | - |
dc.subject.keywordPlus | SIZE | - |
dc.subject.keywordAuthor | gold nanoparticle | - |
dc.subject.keywordAuthor | glycation | - |
dc.subject.keywordAuthor | collagen | - |
dc.subject.keywordAuthor | dermis | - |
dc.subject.keywordAuthor | aging | - |
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