Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Rapid Determination of Volatile Organic Compounds in Human Whole Blood Using Static Headspace Sampling with Gas Chromatography and Mass Spectrometry

Authors
Lee, Ji-YoungKim, SeungkiLee, Jong-TaeChoi, Jong-HoLee, JeongaePyo, Heesoo
Issue Date
20-12월-2012
Publisher
KOREAN CHEMICAL SOC
Keywords
VOCs; Whole blood; Headspace; HS-GC-MS
Citation
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.33, no.12, pp.3963 - 3970
Indexed
SCIE
SCOPUS
KCI
Journal Title
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
Volume
33
Number
12
Start Page
3963
End Page
3970
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/106642
DOI
10.5012/bkcs.2012.33.12.3963
ISSN
0253-2964
Abstract
Headspace (HS) and headspace solid-phase microextraction (HS-SPME) were studied for extracting volatile organic compounds (VOCs) from whole blood, with chemical and instrumental variables being optimized for maximum sensitivity: incubation at 60 degrees C, equilibration for 30 mm, pH 11, and 2 mL injection volume. Both techniques provided accurate analyses, with detection limits of 0.05-0.1 ng mL(-1) and 0.05-0.5 ng mL(-1). HS showed better sensitivity, reproducibility, and analysis times than HS-SPME. Overall levels of chloroform in whole blood were found to be 0.05-5.84 ng mL(-1); detected levels of benzene were 0.05-2.20 ng mL(-1).
Files in This Item
There are no files associated with this item.
Appears in
Collections
Graduate School > Department of Public Health Sciences > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Lee, Jong Tae photo

Lee, Jong Tae
보건과학과
Read more

Altmetrics

Total Views & Downloads

BROWSE