Nanoencapsulation of Drug-loaded Lipid by Temperature-induced Phase Transition
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, H. | - |
dc.contributor.author | Kim, J. Y. | - |
dc.contributor.author | Koo, E. J. | - |
dc.contributor.author | Lee, J. | - |
dc.contributor.author | Lee, E. H. | - |
dc.contributor.author | Oh, K. S. | - |
dc.contributor.author | Yuk, S. H. | - |
dc.date.accessioned | 2021-09-06T12:31:11Z | - |
dc.date.available | 2021-09-06T12:31:11Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2012-12 | - |
dc.identifier.issn | 0352-9568 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/106785 | - |
dc.description.abstract | Pluronic nanoparticles (NPs) were prepared by means of a temperature-induced phase transition in the mixture composed of Pluronic F-68 and liquid Tween 80/soybean oil containing model drugs such as orlistat, caffeine, and ibuprofen sodium salt. Liquid soybean oil/Tween 80 was used as a solubilizer for model drugs, and Pluronic F-68 was the polymer that stabilizes liquid soybean oil/Tween 80 containing model drugs. Field-emission scanning electron microscopy and particle size analyzer were used to observe the morphology and size distribution of the prepared NPs. X-ray diffractometer was used to understand relationship between the crystalline state of the model drug and its solubility in the aqueous media. To observe the feasibility of Pluronic NPs as a drug delivery system, the release pattern of model drugs was observed. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | CROATIAN SOC CHEMICAL ENGINEERING TECHNOLOGY | - |
dc.subject | NANOPARTICLES | - |
dc.subject | IBUPROFEN | - |
dc.subject | RELEASE | - |
dc.title | Nanoencapsulation of Drug-loaded Lipid by Temperature-induced Phase Transition | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, E. H. | - |
dc.contributor.affiliatedAuthor | Yuk, S. H. | - |
dc.identifier.scopusid | 2-s2.0-84874913321 | - |
dc.identifier.wosid | 000314256800009 | - |
dc.identifier.bibliographicCitation | CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY, v.26, no.4, pp.385 - 390 | - |
dc.relation.isPartOf | CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY | - |
dc.citation.title | CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY | - |
dc.citation.volume | 26 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 385 | - |
dc.citation.endPage | 390 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Engineering, Chemical | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | IBUPROFEN | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordAuthor | Nanoencapsulation | - |
dc.subject.keywordAuthor | pluronic | - |
dc.subject.keywordAuthor | temperature - induced phase transition | - |
dc.subject.keywordAuthor | solubility | - |
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