Inhibition of Biofilm Formation on Ventilation Tubes by Surface Modification
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Song, Jae-Jun | - |
dc.contributor.author | Noh, Insup | - |
dc.contributor.author | Chae, Sung-Won | - |
dc.date.accessioned | 2021-09-06T13:42:40Z | - |
dc.date.available | 2021-09-06T13:42:40Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2012-11 | - |
dc.identifier.issn | 0258-851X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/107026 | - |
dc.description.abstract | Aim: The purpose of this study was to modify the surface characteristics of a ventilation tube (VT) with polyethylene glycol (PEG) coating and to evaluate the effect on biofilm formation. Materials and Methods: VTs made of polyethylene were coated with PEG. Streptococcus pneumonia R6 strain was used and a crystal violet assay was carried out to measure the in vitro and in vivo biofilm formation of rats bearing VTs. Results: In the in vitro experiment, the optical density of the uncoated VT was 0.34 +/- 0.09 and the optical density of the PEG-grafted VT was 0.22 +/- 0.06 (p<0.05). In the in vivo experiment, the optical density of the uncoated VT was 0.54 +/- 0.12 and that of the PEG-grafted VT was 0.32 +/- 0.13 (p<0.05). Scanning electron microscopy showed that surface modification, roughness and hydrophilic characteristics improved and biofilm formation decreased. Conclusion: The reduced biofilm formation on the VT may be explained by the alteration of surface tension and roughness induced by PEG coating. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | INT INST ANTICANCER RESEARCH | - |
dc.subject | MIDDLE-EAR MUCOSA | - |
dc.subject | TYMPANOSTOMY-TUBE | - |
dc.subject | OTITIS-MEDIA | - |
dc.subject | BACTERIAL BIOFILMS | - |
dc.subject | IN-VIVO | - |
dc.subject | RESISTANCE | - |
dc.subject | ROUGHNESS | - |
dc.subject | CHILDREN | - |
dc.subject | TREAT | - |
dc.subject | MODEL | - |
dc.title | Inhibition of Biofilm Formation on Ventilation Tubes by Surface Modification | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chae, Sung-Won | - |
dc.identifier.scopusid | 2-s2.0-84872190856 | - |
dc.identifier.wosid | 000311770900005 | - |
dc.identifier.bibliographicCitation | IN VIVO, v.26, no.6, pp.907 - 911 | - |
dc.relation.isPartOf | IN VIVO | - |
dc.citation.title | IN VIVO | - |
dc.citation.volume | 26 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 907 | - |
dc.citation.endPage | 911 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.subject.keywordPlus | MIDDLE-EAR MUCOSA | - |
dc.subject.keywordPlus | TYMPANOSTOMY-TUBE | - |
dc.subject.keywordPlus | OTITIS-MEDIA | - |
dc.subject.keywordPlus | BACTERIAL BIOFILMS | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | RESISTANCE | - |
dc.subject.keywordPlus | ROUGHNESS | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | TREAT | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordAuthor | Biofilm | - |
dc.subject.keywordAuthor | ventilation tube | - |
dc.subject.keywordAuthor | PEG coating | - |
dc.subject.keywordAuthor | streptococcus pneumoniae R6 | - |
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