Is Pursuit of Termination of Atrial Fibrillation During Catheter Ablation of Great Value in Patients with Longstanding Persistent Atrial Fibrillation?
- Authors
- Park, Yae M.; Choi, Jong-Il; Lim, Hong E.; Park, Sang W.; Kim, Young-Hoon
- Issue Date
- 10월-2012
- Publisher
- WILEY
- Keywords
- atrial tachycardia; catheter ablation; complex fractionated atrial electrograms; left atrial flutter; persistent atrial fibrillation; pulmonary vein isolation
- Citation
- JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, v.23, no.10, pp.1051 - 1058
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
- Volume
- 23
- Number
- 10
- Start Page
- 1051
- End Page
- 1058
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/107249
- DOI
- 10.1111/j.1540-8167.2012.02370.x
- ISSN
- 1045-3873
- Abstract
- Termination of Atrial Fibrillation During Catheter Ablation Predicts Better Outcome. Background: The reliable endpoint for ablation of longstanding persistent atrial fibrillation (LPAF) has not been clearly established. Methods and Results: This study included 140 patients who underwent catheter ablation for drug-refractory LPAF. A stepwise ablation approach included circumferential pulmonary vein isolation followed by left atrial and right atrial complex fractionated electrogram-guided ablation. Atrial fibrillation (AF) was terminated by radiofrequency application during catheter ablation in 95 patients (67.9%). Among them, 33 patients (23.6%) converted to sinus rhythm directly, whereas 62 patients (44.3%) via atrial tachycardias (ATs). Patients in whom AF terminated during the index procedure had a lower recurrence rate of atrial arrhythmia than patients in whom AF did not terminate (45.3% vs 68.9%, P = 0.009, follow-up 18.7 +/- 7.6 months). Among patients in whom AF terminated, there was no significant difference in recurrence rate according to the termination mode, whether converted to AT or not (P = NS). However, patients who converted to AT had a higher recurrence rate of AT (54.8% vs 81%; P = 0.016). Multivariable logistic regression analysis demonstrated that termination of AF during ablation (HR 0.440; 95% CI: 0.2000.969, P = 0.041) and structural heart disease (HR 2.633; 95% CI: 1.2115.723; P = 0.015) were significant independent factors predicting the recurrence of atrial arrhythmia. Conclusions: Termination of AF during catheter ablation is associated with a better clinical outcome in patients with LPAF. (J Cardiovasc Electrophysiol, Vol. 23 pp. 1051-1058, October 2012)
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
- College of Medicine > Department of Medical Science > 1. Journal Articles
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