Allogeneic Hematopoietic Stem Cell Transplant for Adults over 40 Years Old with Acquired Aplastic Anemia
DC Field | Value | Language |
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dc.contributor.author | Kim, Hawk | - |
dc.contributor.author | Lee, Kyoo-Hyung | - |
dc.contributor.author | Yoon, Sung-Soo | - |
dc.contributor.author | Sohn, Sang Kyun | - |
dc.contributor.author | Joo, Young Don | - |
dc.contributor.author | Kim, Sung Hyun | - |
dc.contributor.author | Kim, Byung Soo | - |
dc.contributor.author | Choi, Jung Hye | - |
dc.contributor.author | Kwak, Jae Youg | - |
dc.contributor.author | Hyun, Myung Soo | - |
dc.contributor.author | Bae, Sung Hwa | - |
dc.contributor.author | Shin, Ho Jin | - |
dc.contributor.author | Won, Jong Ho | - |
dc.contributor.author | Oh, Sukjoong | - |
dc.contributor.author | Lee, Won Sik | - |
dc.contributor.author | Park, Jae-Hoo | - |
dc.contributor.author | Jung, Chul Won | - |
dc.date.accessioned | 2021-09-06T14:45:54Z | - |
dc.date.available | 2021-09-06T14:45:54Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2012-10 | - |
dc.identifier.issn | 1083-8791 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/107253 | - |
dc.description.abstract | Although younger age is associated with favorable prognosis in adults undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) for aplastic anemia (AA), other pretransplantation factors may be more important than age. We retrospectively analyzed the impact of older age on transplantation outcomes and survival in a total of 225 adult patients with AA who underwent allo-HSCT: 57 patients >40 years old (older patient group [OPG]) and 168 patients <= 40 years old (younger patient group [YPG]). Age at allo-HSCT <= 40 years, time from diagnosis to allo-HSCT <= 6 months, and matched related donor (MRD) were favorable prognostic factors in all study patients. Risk analysis of survival in the OPG showed that age >50 years was the only poor prognostic factor. Survival did not differ significantly between the YPG and patients <50 years old in the OPG. In conclusion, patients between the ages of 41 and 50 years with severe AA and MRDs should undergo allo-HSCT as early as possible to optimize survival. Biol Blood Marrow Transplant 18: 1500-1508 (2012) (C) 2012 American Society fir Blood and Marrow Transplantation | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | BONE-MARROW-TRANSPLANTATION | - |
dc.subject | TOTAL-BODY IRRADIATION | - |
dc.subject | CYCLOPHOSPHAMIDE | - |
dc.subject | FLUDARABINE | - |
dc.subject | DISEASE | - |
dc.title | Allogeneic Hematopoietic Stem Cell Transplant for Adults over 40 Years Old with Acquired Aplastic Anemia | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Byung Soo | - |
dc.identifier.doi | 10.1016/j.bbmt.2012.03.015 | - |
dc.identifier.scopusid | 2-s2.0-84866172587 | - |
dc.identifier.wosid | 000309314100006 | - |
dc.identifier.bibliographicCitation | BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, v.18, no.10, pp.1500 - 1508 | - |
dc.relation.isPartOf | BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | - |
dc.citation.title | BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | - |
dc.citation.volume | 18 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1500 | - |
dc.citation.endPage | 1508 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Hematology | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Transplantation | - |
dc.relation.journalWebOfScienceCategory | Hematology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Transplantation | - |
dc.subject.keywordPlus | BONE-MARROW-TRANSPLANTATION | - |
dc.subject.keywordPlus | TOTAL-BODY IRRADIATION | - |
dc.subject.keywordPlus | CYCLOPHOSPHAMIDE | - |
dc.subject.keywordPlus | FLUDARABINE | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordAuthor | Aplastic anemia | - |
dc.subject.keywordAuthor | Allogeneic hematopoietic stem cell transplantation | - |
dc.subject.keywordAuthor | Elderly | - |
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