Tumor-targeting multi-functional nanoparticles for theragnosis: New paradigm for cancer therapy
- Authors
- Ryu, Ju Hee; Koo, Heebeom; Sun, In-Cheol; Yuk, Soon Hong; Choi, Kuiwon; Kim, Kwangmeyung; Kwon, Ick Chan
- Issue Date
- 10월-2012
- Publisher
- ELSEVIER SCIENCE BV
- Keywords
- Theragnosis; Chemotherapy; Photodynamic therapy; siRNA therapy; Photothermal therapy; Optical imaging; Personalized medicine; Molecular imaging; Cancer; Nanomedicine
- Citation
- ADVANCED DRUG DELIVERY REVIEWS, v.64, no.13, pp.1447 - 1458
- Indexed
- SCIE
SCOPUS
- Journal Title
- ADVANCED DRUG DELIVERY REVIEWS
- Volume
- 64
- Number
- 13
- Start Page
- 1447
- End Page
- 1458
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/107339
- DOI
- 10.1016/j.addr.2012.06.012
- ISSN
- 0169-409X
- Abstract
- Theragnostic nanoparticles (NPs) contain diagnostic and therapeutic functions in one integrated system, enabling diagnosis, therapy, and monitoring of therapeutic response at the same time. For diagnostic function, theragnostic NPs require the inclusion of noninvasive imaging modalities. Among them, optical imaging has various advantages including sensitivity, real-time and convenient use, and non-ionization safety, which make it the leading technique for theragnostic NPs. For therapeutic function, theragnostic NPs have been applied to chemotherapy, photodynamic therapy, siRNA therapy and photothermal therapy. In this review, we present a recent progress reported in the development and applications of theragnostic NPs for cancer therapy. More specifically, we will focus on theragnostic NPs related with optical imaging, highlighting promising strategies based on optical imaging techniques. (C) 2012 Elsevier B.V. All rights reserved.
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- Appears in
Collections - College of Pharmacy > Department of Pharmaceutical Science > 1. Journal Articles
- Graduate School > KU-KIST Graduate School of Converging Science and Technology > 1. Journal Articles
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