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Microfluidic Spinning of Flat Alginate Fibers with Grooves for Cell-Aligning Scaffolds

Authors
Kang, EdwardChoi, Yoon YoungChae, Su-KyoungMoon, Jin-HeeChang, Joon-YoungLee, Sang-Hoon
Issue Date
16-8월-2012
Publisher
WILEY-V C H VERLAG GMBH
Keywords
microfluidic spinning; fibers; microstructures; patterned; ribbons; grooved; cell alignment; alginates
Citation
ADVANCED MATERIALS, v.24, no.31, pp.4271 - +
Indexed
SCIE
SCOPUS
Journal Title
ADVANCED MATERIALS
Volume
24
Number
31
Start Page
4271
End Page
+
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/107694
DOI
10.1002/adma.201201232
ISSN
0935-9648
Abstract
Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.
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