Associations between gene polymorphisms and rheumatoid arthritis: a meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Lee, Young Ho | - |
dc.contributor.author | Bae, Sang-Cheol | - |
dc.contributor.author | Choi, Sung Jae | - |
dc.contributor.author | Ji, Jong Dae | - |
dc.contributor.author | Song, Gwan Gyu | - |
dc.date.accessioned | 2021-09-06T19:00:59Z | - |
dc.date.available | 2021-09-06T19:00:59Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2012-06 | - |
dc.identifier.issn | 1023-3830 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/108210 | - |
dc.description.abstract | The aim of this study was to determine whether tumor necrosis factor alpha inducible protein 3 () polymorphisms confer susceptibility to rheumatoid arthritis (RA) in ethnically different populations. The authors conducted meta-analyses on associations between the polymorphisms and RA susceptibility. A total of ten comparative studies were included in this meta-analysis, which showed an association between the two allele of rs6920220 and RA in all study subjects [odds ratio (OR) 1.216, 95% confidence interval (CI) 1.166-1.269, < 1.0 x 10(-9)]. The two allele of rs6920220 was also significantly associated with RA in Europeans only (OR 1.227, 95% CI 1.175-1.282, < 1.0 x 10(-9)). Meta-analysis revealed no association between the two allele of the rs10499194 polymorphism and RA in Europeans, but a significant association was found in Asians (OR 1.254, 95% CI 1.101-1.429, = 6.7 x 10(-4)). Furthermore, an association was found between the two allele of rs2230926 and RA in all study subjects (OR 1.390, 95% CI 1.214-2.331, = 1.9 x 10(-6)). This meta-analysis confirms that the polymorphisms are associated with RA susceptibility in different ethnic groups, namely, in Europeans for rs6920220 and in Asians for rs10499194. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER BASEL AG | - |
dc.subject | SYSTEMIC-LUPUS-ERYTHEMATOSUS | - |
dc.subject | AUTOIMMUNE-DISEASES | - |
dc.subject | KAPPA-B | - |
dc.subject | TNFAIP3 | - |
dc.subject | SUSCEPTIBILITY | - |
dc.subject | COMMON | - |
dc.subject | 6Q23 | - |
dc.subject | POPULATION | - |
dc.subject | RESPONSES | - |
dc.subject | VARIANTS | - |
dc.title | Associations between gene polymorphisms and rheumatoid arthritis: a meta-analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Young Ho | - |
dc.contributor.affiliatedAuthor | Choi, Sung Jae | - |
dc.identifier.doi | 10.1007/s00011-012-0455-5 | - |
dc.identifier.scopusid | 2-s2.0-84865137693 | - |
dc.identifier.wosid | 000303820100013 | - |
dc.identifier.bibliographicCitation | INFLAMMATION RESEARCH, v.61, no.6, pp.635 - 641 | - |
dc.relation.isPartOf | INFLAMMATION RESEARCH | - |
dc.citation.title | INFLAMMATION RESEARCH | - |
dc.citation.volume | 61 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 635 | - |
dc.citation.endPage | 641 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | SYSTEMIC-LUPUS-ERYTHEMATOSUS | - |
dc.subject.keywordPlus | AUTOIMMUNE-DISEASES | - |
dc.subject.keywordPlus | KAPPA-B | - |
dc.subject.keywordPlus | TNFAIP3 | - |
dc.subject.keywordPlus | SUSCEPTIBILITY | - |
dc.subject.keywordPlus | COMMON | - |
dc.subject.keywordPlus | 6Q23 | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | RESPONSES | - |
dc.subject.keywordPlus | VARIANTS | - |
dc.subject.keywordAuthor | Tumor necrosis factor alpha inducible protein 3 | - |
dc.subject.keywordAuthor | Polymorphism | - |
dc.subject.keywordAuthor | Rheumatoid arthritis | - |
dc.subject.keywordAuthor | Meta-analysis | - |
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