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The relationship between fat depot-specific preadipocyte differentiation and metabolic syndrome in obese women
- Authors
- Park, Hyun Tae; Lee, Eun Sil; Cheon, Yong-Pil; Lee, Dong Ryul; Yang, Kyung-Sook; Kim, Young Tae; Hur, Jun Young; Kim, Sun Haeng; Lee, Kyu Wan; Kim, Tak
- Issue Date
- 1월-2012
- Publisher
- WILEY
- Citation
- CLINICAL ENDOCRINOLOGY, v.76, no.1, pp.59 - 66
- Indexed
- SCIE
SCOPUS
- Journal Title
- CLINICAL ENDOCRINOLOGY
- Volume
- 76
- Number
- 1
- Start Page
- 59
- End Page
- 66
- ISSN
- 0300-0664
- Abstract
- Objective Obesity is strongly associated with metabolic syndrome, but not all obese individuals display a clustering of metabolic risk factors. Recent studies have shown that in vitro subcutaneous (SC)-preadipocyte differentiation is negatively associated with obesity. These results suggest that impaired adipogenesis is an important factor linking obesity to metabolic disorders. We examined whether in vitro preadipocyte differentiation is associated with metabolic syndrome, independent of obesity.
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