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Response patterns to bronchodilator and quantitative computed tomography in chronic obstructive pulmonary disease

Authors
Lee, Jae SeungHuh, Jin WonChae, Eun JinSeo, Joon BeomRa, Seung WonLee, Ji-HyunKim, Eun-KyungLee, Young KyungKim, Tae-HyungKim, Woo JinLee, Jin HwaLee, Sang-MinLee, SangyeubLim, Seong YongShin, Tae RimYoon, Ho IlSheen, Seung SooOh, Yeon-MokLee, Sang-Do
Issue Date
1월-2012
Publisher
WILEY
Keywords
bronchodilators; chronic obstructive pulmonary disease; emphysema; salbutamol; volumetric computed tomography
Citation
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, v.32, no.1, pp.12 - 18
Indexed
SCIE
SCOPUS
Journal Title
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
Volume
32
Number
1
Start Page
12
End Page
18
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/109192
DOI
10.1111/j.1475-097X.2011.01046.x
ISSN
1475-0961
Abstract
Background: Patients with chronic obstructive pulmonary disease (COPD) show different spirometric response patterns to bronchodilator, such that some patients show improvement principally in expiratory flow (forced expiratory volume in 1 s; FEV1), whereas others respond by improvement of lung volume (forced vital capacity; FVC). The mechanisms of these different response patterns to bronchodilator remain unclear. We investigated the associations between bronchodilator responsiveness and quantitative computed tomography (CT) indices in patients with COPD.
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