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A highly sensitive two-photon fluorescent probe for mitochondrial zinc ions in living tissue
- Authors
- Baek, Na Young; Heo, Cheol Ho; Lim, Chang Su; Masanta, Goutam; Cho, Bong Rae; Kim, Hwan Myung
- Issue Date
- 2012
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- CHEMICAL COMMUNICATIONS, v.48, no.38, pp.4546 - 4548
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMICAL COMMUNICATIONS
- Volume
- 48
- Number
- 38
- Start Page
- 4546
- End Page
- 4548
- ISSN
- 1359-7345
- Abstract
- We report a highly sensitive two-photon probe (SZn2-Mito) which shows a 70-fold two-photon excited fluorescence enhancement in response to Zn2+ and can selectively detect mitochondrial Zn2+ in a rat hippocampal slice at a depth of 100-200 mu m by using two-photon microscopy.
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