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Corticosteroid Treatment of Pure Red Cell Aplasia in a Patient with Hepatitis A
- Issue Date
- 2012
- Publisher
- KARGER
- Keywords
- Anemia; Corticosteroid; Hemolytic anemia; Hepatitis A; Pure red cell aplasia
- Citation
- ACTA HAEMATOLOGICA, v.128, no.1, pp.60 - 63
- Indexed
- SCIE
SCOPUS
- Journal Title
- ACTA HAEMATOLOGICA
- Volume
- 128
- Number
- 1
- Start Page
- 60
- End Page
- 63
- ISSN
- 0001-5792
- Abstract
- Secondary pure red cell aplasia (PRCA), as an extrahepatic manifestation of hepatitis A virus infection, has been reported on rare occasions. We report herein an unusual case of hepatitis A complicated by PRCA. In addition, we reviewed nine cases reported in the English literature. Our case of non-fulminant hepatitis A complicated by PRCA and hemolytic anemia was successfully treated with initial transfusion and corticosteroid therapy for 18 weeks. The patient's hematologic abnormalities and liver function tests re-normalized completely. We review clinical features and effective therapeutic strategies for this disease entity. Copyright (C) 2012 S. Karger AG, Basel
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Related Researcher
- Yoon, Young Kyung
- College of Medicine (Department of Medical Science)