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A versatile assay for monitoring in vivo-like transendothelial migration of neutrophils

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dc.contributor.authorHan, Sewoon-
dc.contributor.authorYan, Ji-Jing-
dc.contributor.authorShin, Yoojin-
dc.contributor.authorJeon, Jessie S.-
dc.contributor.authorWon, Jihee-
dc.contributor.authorJeong, Hyo Eun-
dc.contributor.authorKamm, Roger D.-
dc.contributor.authorKim, Young-Joon-
dc.contributor.authorChung, Seok-
dc.date.accessioned2021-09-07T00:20:10Z-
dc.date.available2021-09-07T00:20:10Z-
dc.date.created2021-06-18-
dc.date.issued2012-
dc.identifier.issn1473-0197-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/109472-
dc.description.abstractSpatiotemporal analysis of the inflammatory response has been limited by the difficulties of in vivo imaging and reconstitution of inflammation in vitro. Here, we present a novel method for establishing in vivo-like inflammatory models in a microfluidic device and quantitatively measuring the three-dimensional transmigration of neutrophils during the inflammatory process. This enabled us to concurrently characterize transendothelial migration behaviors of neutrophils under the influence of various inflammatory stimuli.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectENDOTHELIAL-CELLS-
dc.subjectMICROFLUIDIC PLATFORM-
dc.subjectLYMPHOCYTE MIGRATION-
dc.subjectCOLLAGEN GEL-
dc.subjectTUMOR-CELLS-
dc.subjectTRANSMIGRATION-
dc.subjectINFLAMMATION-
dc.subjectDIFFUSION-
dc.subjectANGIOGENESIS-
dc.subjectMETASTASIS-
dc.titleA versatile assay for monitoring in vivo-like transendothelial migration of neutrophils-
dc.typeArticle-
dc.contributor.affiliatedAuthorChung, Seok-
dc.identifier.doi10.1039/c2lc40445a-
dc.identifier.scopusid2-s2.0-84873707878-
dc.identifier.wosid000308894600003-
dc.identifier.bibliographicCitationLAB ON A CHIP, v.12, no.20, pp.3861 - 3865-
dc.relation.isPartOfLAB ON A CHIP-
dc.citation.titleLAB ON A CHIP-
dc.citation.volume12-
dc.citation.number20-
dc.citation.startPage3861-
dc.citation.endPage3865-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaScience & Technology - Other Topics-
dc.relation.journalResearchAreaInstruments & Instrumentation-
dc.relation.journalWebOfScienceCategoryBiochemical Research Methods-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryChemistry, Analytical-
dc.relation.journalWebOfScienceCategoryNanoscience & Nanotechnology-
dc.relation.journalWebOfScienceCategoryInstruments & Instrumentation-
dc.subject.keywordPlusENDOTHELIAL-CELLS-
dc.subject.keywordPlusMICROFLUIDIC PLATFORM-
dc.subject.keywordPlusLYMPHOCYTE MIGRATION-
dc.subject.keywordPlusCOLLAGEN GEL-
dc.subject.keywordPlusTUMOR-CELLS-
dc.subject.keywordPlusTRANSMIGRATION-
dc.subject.keywordPlusINFLAMMATION-
dc.subject.keywordPlusDIFFUSION-
dc.subject.keywordPlusANGIOGENESIS-
dc.subject.keywordPlusMETASTASIS-
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