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Plexiform Angiomyxoid Myofibroblastic Tumor of the Stomach: Report of Two Cases and Review of the Literature
- Authors
- Kang, Youngran; Jung, Wonkyung; Do, In-Gu; Lee, Eui Jin; Lee, Min Hyeong; Kim, Kyoung-Mee; Choi, Jongsang
- Issue Date
- 2012
- Publisher
- KOREAN SOCIETY PATHOLOGISTS
- Keywords
- Angiomyxoid; Stomach; Myofibroblasts; Plexiform; Prognosis; Review
- Citation
- KOREAN JOURNAL OF PATHOLOGY, v.46, no.3, pp.292 - 296
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- KOREAN JOURNAL OF PATHOLOGY
- Volume
- 46
- Number
- 3
- Start Page
- 292
- End Page
- 296
- ISSN
- 1738-1843
- Abstract
- Plexiform angiomyxoid myofibroblastic tumor (PAMT) of the stomach is a recently recognized entity. Because of its rarity, only 22 cases have been reported in the English-language literature and most of these are single case reports. We report two cases of gastric PAMT. The tumor cells were bland and plexiform arranged in a myxoid stroma, which was positive for alcian blue. Immunohistochemically, the tumor cells were positive for smooth muscle actin, but negative for c-kit, CD34, desmin, S-100 protein, epithelial membrane antigen, neurofilament, and protein kinase C-theta. Mutation analyses for exon 9, 11, 13, and 17 of KIT genes and 12, 14, and 18 of the platelet-derived growth factor receptor alpha (PDGFRA) genes were performed and the tumors were wildtype for mutation.
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