Analysis of Pulsatile and Nonpulsatile Blood Flow Effects in Different Degrees of Stenotic Vasculature
DC Field | Value | Language |
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dc.contributor.author | Jung, Jae Seung | - |
dc.contributor.author | Son, Kuk Hui | - |
dc.contributor.author | Ahn, Chi Bum | - |
dc.contributor.author | Lee, Jung Joo | - |
dc.contributor.author | Son, Ho Sung | - |
dc.contributor.author | Sun, Kyung | - |
dc.date.accessioned | 2021-09-07T06:32:24Z | - |
dc.date.available | 2021-09-07T06:32:24Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2011-11 | - |
dc.identifier.issn | 0160-564X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/111213 | - |
dc.description.abstract | Vessel lumens that have been chronically narrowed by atherosclerosis should be increased in flow velocity and intrastenotic area pressure to maintain an equal flow. This might be followed by a decrease in hemodynamic energy, leading to a reduction of tissue perfusion. In this study, we compared hemodynamic energies according to degrees of stenotic vasculature between pulsatile flow and nonpulsatile flow. Cannuale with 25, 50, and 75% diameter stenosis (DS) were located at the outlet cannula. Using the Korea Hybrid ventricular assist device (KH-VAD) (pulsatile pump: group A) and Biopump (nonpulsatile pump: group B), constant flow of 2 L/min was maintained then real-time flow and velocity in the proximal and distal part of the stenotic cannula were measured. The hemodynamic energies of two groups were compared. At 75% DS, proximal energy equivalent pressure (EEP) delivered to the distal end was only 41.9% (group A) and 42.5% (group B). As the percent EEP fell below 10%, pulsatility disappeared from the 50% stenosis in group A. The surplus hemodynamic energy (SHE) of group B at all degrees of stenosis must have been 0, which was also the case of group A at 75% stenosis. This research evaluated the hemodynamic energy on various degrees of DS in both pulsatile and nonpulsatile flow with mock system. Using a pulsatile pump, pulsatility disappeared above 50% DS while hemodynamic energy was maintained. Therefore, our results suggest that pulsatile flow has a better effect than nonpulsatile flow in reserving hemodynamic energy after stenotic lesion. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.subject | CARDIOPULMONARY BYPASS | - |
dc.title | Analysis of Pulsatile and Nonpulsatile Blood Flow Effects in Different Degrees of Stenotic Vasculature | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, Jae Seung | - |
dc.contributor.affiliatedAuthor | Ahn, Chi Bum | - |
dc.contributor.affiliatedAuthor | Lee, Jung Joo | - |
dc.contributor.affiliatedAuthor | Son, Ho Sung | - |
dc.contributor.affiliatedAuthor | Sun, Kyung | - |
dc.identifier.doi | 10.1111/j.1525-1594.2011.01361.x | - |
dc.identifier.scopusid | 2-s2.0-81855204971 | - |
dc.identifier.wosid | 000297201200021 | - |
dc.identifier.bibliographicCitation | ARTIFICIAL ORGANS, v.35, no.11, pp.1118 - 1122 | - |
dc.relation.isPartOf | ARTIFICIAL ORGANS | - |
dc.citation.title | ARTIFICIAL ORGANS | - |
dc.citation.volume | 35 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1118 | - |
dc.citation.endPage | 1122 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Transplantation | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Transplantation | - |
dc.subject.keywordPlus | CARDIOPULMONARY BYPASS | - |
dc.subject.keywordAuthor | Pulsatile flow | - |
dc.subject.keywordAuthor | Extracorporeal circulation | - |
dc.subject.keywordAuthor | Hemodynamic energy | - |
dc.subject.keywordAuthor | Diameter stenosis | - |
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