Multiphoton microscopy: An introduction to gastroenterologists
- Authors
- Cho, Hye Jin; Chun, Hoon Jai; Kim, Eun Sun; Cho, Bong Rae
- Issue Date
- 28-10월-2011
- Publisher
- BAISHIDENG PUBLISHING GROUP INC
- Keywords
- Multiphoton microscopy; Optical biopsy; Gastrointestinal disease
- Citation
- WORLD JOURNAL OF GASTROENTEROLOGY, v.17, no.40, pp.4456 - 4460
- Indexed
- SCIE
SCOPUS
- Journal Title
- WORLD JOURNAL OF GASTROENTEROLOGY
- Volume
- 17
- Number
- 40
- Start Page
- 4456
- End Page
- 4460
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/111346
- DOI
- 10.3748/wjg.v17.i40.4456
- ISSN
- 1007-9327
- Abstract
- Multiphoton microscopy, relying on the simultaneous absorption of two or more photons by a fluorophore, has come to occupy a prominent place in modern biomedical research with its ability to allow real-time observation of a single cell and molecules in intact tissues. Multiphoton microscopy exhibits nonlinear optical contrast properties, which can make it possible to provide an exceptionally large depth penetration with less phototoxicity. This system becomes more and more an inspiring tool for a non-invasive imaging system to realize "optical biopsy" and to examine the functions of living cells. In this review, we briefly present the physical principles and properties of multiphoton microscopy as well as the current applications in biological fields. In addition, we address what we see as the future potential of multiphoton microscopy for gastroenterologic research. (C) 2011 Baishideng. All rights reserved.
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- Appears in
Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- College of Science > Department of Chemistry > 1. Journal Articles
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