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Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union

Authors
Choi, Kang KookChoi, Sae ByeolPark, Seung WooKim, Hyun KiPark, Young NyunKim, Kyung Sik
Issue Date
10월-2011
Publisher
KOREAN SURGICAL SOCIETY
Keywords
Choledochal cyst; Gallbladder neoplsms; Bile duct neoplasms; Synchronous multiple primary neoplasms
Citation
JOURNAL OF THE KOREAN SURGICAL SOCIETY, v.81, no.4, pp.281 - 286
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF THE KOREAN SURGICAL SOCIETY
Volume
81
Number
4
Start Page
281
End Page
286
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/111450
DOI
10.4174/jkss.2011.81.4.281
ISSN
2233-7903
Abstract
A 60-year-old female was admitted with epigastric pain lasting a month. Preoperative diagnosis was choledochal cyst with anomalous pancreaticobiliaryductal union (APBDU), C-P type. A papillary mass measuring 2.5 x 1.9 cm was found adjacent to the pancreaticocholedochal junction. Gallbladder (GB) cancer was also observed. Pyloric-preserving pancreaticoduodenectomy (PPPD) was performed. The patient received adjuvant chemotherapy/radiation therapy on the tumor bed. The gallbladder cancer showed serosal invasion, while the bile duct cancer extended into the pancreas. Although common bile duct (CBD) cancer lesion showed focally positive for p53 and the gallbladder cancer lesion showed negative for p53, the Ki-67 labeling index of the CBD cancer and GB cancer were about 10% and 30%, respectively. Nine months after curative resection, a stricture on the subhepatic colon developed due to adjuvant radiation therapy. Localized peritoneal seedings were incidentally found during a right hemicolectomy. The patient underwent chemotherapy and had no evidence of tumor recurrence for two years after PPPD.
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Choi, Sae Byeol
의과대학 (의학과)
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