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An amorphane sesquiterpene and a benzofuran glucoside from Eupatorium coelestinum
- Authors
- Dan Thi Thuy Hang; Tran Thi Hong Hanh; Chau Van Minh; Phan Van Kiem; Tran Huy Thai; Lee, Dongho; Nguyen Tien Dat
- Issue Date
- Sep-2011
- Publisher
- ELSEVIER
- Keywords
- Eupatorium coelestinum; Asteraceae; Amorphane sesquiterpene; Benzofuran; NF-kappa B
- Citation
- PHYTOCHEMISTRY LETTERS, v.4, no.3, pp.377 - 379
- Indexed
- SCIE
SCOPUS
- Journal Title
- PHYTOCHEMISTRY LETTERS
- Volume
- 4
- Number
- 3
- Start Page
- 377
- End Page
- 379
- ISSN
- 1874-3900
- Abstract
- A phytochemical investigation of the aerial parts of Eupatorium coelestinum led to the isolation of an amorphane sesquiterpene and a benzofuran glucoside. By means of spectroscopic methods, their structures were determined as 5 alpha,8 alpha-epoxy-4 alpha,6 beta-dihydroxyamorphan-2-one (1) and 2R*,3S*-toxol-7-O-beta-D-glucopyranoside (2). Compounds 1 significantly inhibited NF-kappa B activity in TNF-alpha-stimulated HeLa cells with the IC50 of 12.4 mu M. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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Collections - Graduate School > Department of Plant Biotechnology > 1. Journal Articles
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Related Researcher
- Lee, Dong ho
- Department of Plant Biotechnology