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Two-Photon Fluorescent Probes for Metal Ions
- Authors
- Kim, Hwan Myung; Cho, Bong Rae
- Issue Date
- 3-1월-2011
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- fluorescent probes; in vivo imaging; metal ions; nonlinear spectroscopy; two-photon microscopy
- Citation
- CHEMISTRY-AN ASIAN JOURNAL, v.6, no.1, pp.58 - 69
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMISTRY-AN ASIAN JOURNAL
- Volume
- 6
- Number
- 1
- Start Page
- 58
- End Page
- 69
- ISSN
- 1861-4728
- Abstract
- Two-photon microscopy (TPM) has become an indispensible tool in biology and medicine owing to the capability of imaging the intact tissue for a long period of time. To make it a versatile tool in biology, a variety of two-photon probes for specific applications are needed. In this context, many research groups are developing two-photon probes for various applications. In this Focus Review, we summarize recent results on model studies and selected examples of two-photon probes that can detect intracellular free metal ions in live cells and tissues to provide a guideline for the design of useful two-photon probes for various in vivo imaging applications.
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