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Fabrication and compressive strength of porous hydroxyapatite scaffolds with a functionally graded core/shell structure
- Authors
- Soon, Young-Mi; Shin, Kwan-Ha; Koh, Young-Hag; Lee, Jong-Hoon; Choi, Won-Young; Kim, Hyoun-Ee
- Issue Date
- 1월-2011
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Suspensions; Porosity; Mechanical properties; Apatite; Biomedical applications
- Citation
- JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, v.31, no.1-2, pp.13 - 18
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
- Volume
- 31
- Number
- 1-2
- Start Page
- 13
- End Page
- 18
- ISSN
- 0955-2219
- Abstract
- A novel type of porous hydroxyapatite (HA) scaffolds with a functionally graded core/shell structure was fabricated by freeze casting HA/camphene slurries with various HA contents into fugitive molds containing a graphite template with three dimensionally interconnected pores for the creation of a highly porous core All the fabricated samples had functionally graded core/shell structures with 3-D periodic pore networks in a core surrounded by a relatively dense shell The overall porosity of the sample decreased from 60 to 38 vol% with increasing HA content in the HA/camphene slurry from 20 to 36 vol% due to a decrease in porosity in both the core and shell regions In addition, the compressive strength was improved remarkably from 12 +/- 11 to 32 +/- 3 0 MPa The in vitro cell test using a pre-osteoblast cell line showed that the samples had good biocompatibility (C) 2010 Elsevier Ltd All rights reserved
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Collections - Graduate School > Department of Bioengineering > 1. Journal Articles
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