[Q fever as a cause of acute hepatitis accompanying fever].
- Authors
- Lee, H.J.; Kim, J.H.; Yoon, E.L.; Lee, Y.S.; Yeon, J.E.; Byun, K.S.; Kim, B.H.; Ryu, Y.
- Issue Date
- 2011
- Citation
- The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, v.57, no.3, pp.189 - 193
- Indexed
- SCOPUS
KCI
- Journal Title
- The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
- Volume
- 57
- Number
- 3
- Start Page
- 189
- End Page
- 193
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/114646
- DOI
- 10.4166/kjg.2011.57.3.189
- ISSN
- 1598-9992
- Abstract
- Q fever is a zoonotic infection caused by Coxiella burnetti, which has been previously regarded as an uncommon infectious disease in Korea but is sporadically reported recently. Common manifestations of acute Q fever usually present as influenza-like illness, pneumonia and occasionally hepatitis. Herein, we report 4 cases of acute Q fever as a cause of acute hepatitis and fever. All patients had fever and non-specific symptoms, and laboratory test showed acute hepatitis. Antibody surveys for many virus infections and bacterial cultures were negative. Finally, they were diagnosed acute Q fever by an indirect microimmunofluorescence test. Liver biopsy in 3 patients revealed granuloma including one with typical fibrin-ring. All patients had complete resolution of symptoms and signs with doxycycline treatment. Q fever should be considered in the differential diagnosis of patients with fever of unknown origin with acute hepatitis in Korea.
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