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Skin absorption potential of ZnO nanoparticles

Authors
Kim, S.Y.Jeong, S.H.Lee, E.Y.Park, Y.-H.Bae, H.C.Jang, Y.S.Maeng, E.H.Kim, M.-K.Son, S.W.
Issue Date
2011
Publisher
Kluwer Academic Publishers
Keywords
3D EpiDerm™ model (EPI-200); Absorption; Skin; ZnO
Citation
Toxicology and Environmental Health Sciences, v.3, no.4, pp.258 - 261
Indexed
SCOPUS
Journal Title
Toxicology and Environmental Health Sciences
Volume
3
Number
4
Start Page
258
End Page
261
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/114677
DOI
10.1007/s13530-011-0100-7
ISSN
2005-9752
Abstract
In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the surface charge and different particle size. Assessment of potential of skin absorption was estimated using 3D EpiDerm™ model (EPI-200) as human skin equivalent model (HSEM). This study demonstrated no evidence of significant penetration of ZnO NPs into the HSEM after 24 h exposure. © 2011 Korean Society of Environmental Risk Assessment and Health Science and Springer.
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