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Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Authors
Chon, HyangahLee, SangyeopYoon, Soo-YoungChang, Soo-IkLim, Dong WooChoo, Jaebum
Issue Date
2011
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.47, no.46, pp.12515 - 12517
Indexed
SCIE
SCOPUS
Journal Title
CHEMICAL COMMUNICATIONS
Volume
47
Number
46
Start Page
12515
End Page
12517
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/115002
DOI
10.1039/c1cc15707h
ISSN
1359-7345
Abstract
A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.
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