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An iminocoumarin-Cu(II) ensemble-based chemodosimeter toward thiols
- Issue Date
- 2011
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- CHEMICAL COMMUNICATIONS, v.47, no.18, pp.5142 - 5144
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMICAL COMMUNICATIONS
- Volume
- 47
- Number
- 18
- Start Page
- 5142
- End Page
- 5144
- ISSN
- 1359-7345
- Abstract
- An 'ensemble'-based fluoregenic chemodosimeter 1-Cu(II) for detection of thiols is reported. Complex 1-Cu(II) sensitively senses thiols followed by hydrolysis to give a marked fluorescence enhancement over other amino acids at pH 7.4 under aqueous media. Confocal microscopic imaging of complex 1-Cu(II) is also herewith demonstrated for cellular thiol detection in HepG2 cells.
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Related Researcher
- Kim, Jong Seung
- College of Science (Department of Chemistry)