A Three-Dimensional Nanostructured Array of Protein Nanoparticles
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seo, Hyuk-Seong | - |
dc.contributor.author | Kim, Seong-Eun | - |
dc.contributor.author | Park, Jin-Seung | - |
dc.contributor.author | Lee, Jong-Hwan | - |
dc.contributor.author | Yang, Ki-Yeon | - |
dc.contributor.author | Lee, Heon | - |
dc.contributor.author | Lee, Kyung Eun | - |
dc.contributor.author | Han, Sung-Sik | - |
dc.contributor.author | Lee, Jeewon | - |
dc.date.accessioned | 2021-09-07T22:12:40Z | - |
dc.date.available | 2021-09-07T22:12:40Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2010-12-08 | - |
dc.identifier.issn | 1616-301X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/115125 | - |
dc.description.abstract | Here a novel technique is reported to construct a three-dimensional (3D) array of well-defined and controllable multilayered nanostructures of proteins that is based on alternate layer-by-layer assembly of bacterial protein nanoparticles and DNA on a patterned array of gold dots. This is the first report on protein-based multilayer stacking, which has the following significant advantages over conventional multilayer assemblies: 1) avoiding hazardous chemicals, the multilayer assembly is implemented in aqueous solution under mild temperature and pH conditions over a relatively short period; 2) direct multilayer growth from designated position is possible by controlling the aspect ratio; 3) multicomponent stacking can be easily performed through alternate stacking of different building blocks (in this case protein nanoparticles); and 4) a wide variety of 3D arrays can be constructed using various functionalized protein nanoparticles that are easily prepared through a simple genetic engineering approach. In this study, as a proof of concept, the developed 3D and patterned arrays of protein nanoparticle multilayers are successfully applied to the multiplexed bioassays of breast and colorectal cancer markers. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.subject | THIN-FILMS | - |
dc.subject | DNA | - |
dc.subject | FABRICATION | - |
dc.subject | CANCER | - |
dc.subject | PROTEASOME | - |
dc.subject | EXPRESSION | - |
dc.subject | DEPOSITION | - |
dc.subject | DENSITY | - |
dc.title | A Three-Dimensional Nanostructured Array of Protein Nanoparticles | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Jeewon | - |
dc.identifier.doi | 10.1002/adfm.201001144 | - |
dc.identifier.scopusid | 2-s2.0-78650158141 | - |
dc.identifier.wosid | 000285392900003 | - |
dc.identifier.bibliographicCitation | ADVANCED FUNCTIONAL MATERIALS, v.20, no.23, pp.4055 - 4061 | - |
dc.relation.isPartOf | ADVANCED FUNCTIONAL MATERIALS | - |
dc.citation.title | ADVANCED FUNCTIONAL MATERIALS | - |
dc.citation.volume | 20 | - |
dc.citation.number | 23 | - |
dc.citation.startPage | 4055 | - |
dc.citation.endPage | 4061 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.subject.keywordPlus | THIN-FILMS | - |
dc.subject.keywordPlus | DNA | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | PROTEASOME | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | DEPOSITION | - |
dc.subject.keywordPlus | DENSITY | - |
dc.subject.keywordAuthor | biosensors | - |
dc.subject.keywordAuthor | nanoparticles | - |
dc.subject.keywordAuthor | nanostructures | - |
dc.subject.keywordAuthor | protein engineering | - |
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