Effects of Fermented Ginseng Extracts on Tumor Metastasis in Mice
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Dong Zhou | - |
dc.contributor.author | Liu, Dan | - |
dc.contributor.author | Jo, Seon Yoong | - |
dc.contributor.author | Kang, Tae-Bong | - |
dc.contributor.author | Lee, Jin Moo | - |
dc.contributor.author | Suh, Hyung Joo | - |
dc.contributor.author | Kim, Ae-jung | - |
dc.contributor.author | Yoon, Taek Joon | - |
dc.date.accessioned | 2021-09-07T22:27:32Z | - |
dc.date.available | 2021-09-07T22:27:32Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2010-12 | - |
dc.identifier.issn | 1226-7708 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/115204 | - |
dc.description.abstract | This study was demonstrated that the fermentation of gingseng increases its biological activities, by comparing the anti-tumor and immunostimulating activities of fermented gingseng extracts (FginE) with those of non-fermented ginseng (GinE). In the experimental lung metastasis of colon26-M3.1 carcinoma, the intraperitoneal (i.p.) or peroral (p.o.) administration of FginE showed stronger anti-tumor metastatic activities than those of GinE. When stimulating 2 kinds of extract on macrophages, FginE was shown to have a higher production of interleukin (IL)-12 than GinE. In addition, treatment with FginE induced tumoricidal activity of peritoneal macrophages against colon26-M3.1 cells. When Peyer's patch was co-cultured with FginE, the proliferation of these cells and granulocyte macrophage-colony stimulating factor (GMCSF) production were induced. In an assay for natural killer (NK) cell activity, an i.p. administration of FginE significantly augmented NK cytotoxicity against Yac-1 tumor cells. Fermented ginseng extracts promotes antitumor activities to inhibit tumor metastasis, and its antitumor effects are associated with the enhancement of systemic as well as mucosal immune systems. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST | - |
dc.subject | PROTOPANAXADIOL SAPONINS | - |
dc.subject | INTESTINAL BACTERIA | - |
dc.subject | ANTITUMOR IMMUNITY | - |
dc.subject | PANAX-GINSENG | - |
dc.subject | FATTY-ACID | - |
dc.subject | NK-CELLS | - |
dc.subject | IMMUNOTHERAPY | - |
dc.subject | POLYSACCHARIDES | - |
dc.subject | INTERLEUKIN-12 | - |
dc.subject | GINSENOSIDE-RB2 | - |
dc.title | Effects of Fermented Ginseng Extracts on Tumor Metastasis in Mice | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Suh, Hyung Joo | - |
dc.identifier.doi | 10.1007/s10068-010-0221-9 | - |
dc.identifier.scopusid | 2-s2.0-79959709468 | - |
dc.identifier.wosid | 000285906100020 | - |
dc.identifier.bibliographicCitation | FOOD SCIENCE AND BIOTECHNOLOGY, v.19, no.6, pp.1559 - 1565 | - |
dc.relation.isPartOf | FOOD SCIENCE AND BIOTECHNOLOGY | - |
dc.citation.title | FOOD SCIENCE AND BIOTECHNOLOGY | - |
dc.citation.volume | 19 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1559 | - |
dc.citation.endPage | 1565 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001510215 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.subject.keywordPlus | PROTOPANAXADIOL SAPONINS | - |
dc.subject.keywordPlus | INTESTINAL BACTERIA | - |
dc.subject.keywordPlus | ANTITUMOR IMMUNITY | - |
dc.subject.keywordPlus | PANAX-GINSENG | - |
dc.subject.keywordPlus | FATTY-ACID | - |
dc.subject.keywordPlus | NK-CELLS | - |
dc.subject.keywordPlus | IMMUNOTHERAPY | - |
dc.subject.keywordPlus | POLYSACCHARIDES | - |
dc.subject.keywordPlus | INTERLEUKIN-12 | - |
dc.subject.keywordPlus | GINSENOSIDE-RB2 | - |
dc.subject.keywordAuthor | fermented-ginseng | - |
dc.subject.keywordAuthor | tumor metastasis | - |
dc.subject.keywordAuthor | innate immunity | - |
dc.subject.keywordAuthor | mucosal immunity | - |
dc.subject.keywordAuthor | cytokine | - |
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