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Immunotoxicity activity of the major essential oil of Filipendula glaberrima against Aedes aegypti L
- Authors
- Lee, Sung-Jae; Moon, Hyung-In
- Issue Date
- 12월-2010
- Publisher
- INFORMA HEALTHCARE
- Keywords
- Aedes aegypti; Filipendula glaberrima; major essential oils; immunotoxicity effects
- Citation
- IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, v.32, no.4, pp.617 - 619
- Indexed
- SCIE
SCOPUS
- Journal Title
- IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Volume
- 32
- Number
- 4
- Start Page
- 617
- End Page
- 619
- ISSN
- 0892-3973
- Abstract
- The aerial parts of Filipendula glaberrima were extracted and the composition and immunotoxicity effects of major essential oils were studied. The analyses conducted by gas chromatography and mass spectroscopy (GC-MS) revealed the essential oils of F. glaberrima. The F. glaberrima essential oil (FGEO) yield was 0.046%, and GC/MS analysis revealed that its major constituents were beta-farnesol (2.96%), l-alpha-terpineol (2.43%), benzenemethanol (2.87%), (Z)-3-hexen-1-ol (5.23%), and 2,6-bis(1,1-dimethylethyl)-4-methylphenol (1.91%). The essential oil had a significant toxic effect against early fourth stage larvae of Aedes aegypti L with an LC(50) value of 28.43 ppm and an LC(90) value of 76.21 ppm. The results could be useful in search for newer, safer, and more effective natural immunotoxicity agents against A. aegypti.</.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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