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Immunotoxicity activity of the major essential oil of Filipendula glaberrima against Aedes aegypti L

Authors
Lee, Sung-JaeMoon, Hyung-In
Issue Date
Dec-2010
Publisher
INFORMA HEALTHCARE
Keywords
Aedes aegypti; Filipendula glaberrima; major essential oils; immunotoxicity effects
Citation
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, v.32, no.4, pp.617 - 619
Indexed
SCIE
SCOPUS
Journal Title
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
Volume
32
Number
4
Start Page
617
End Page
619
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/115246
DOI
10.3109/08923971003652983
ISSN
0892-3973
Abstract
The aerial parts of Filipendula glaberrima were extracted and the composition and immunotoxicity effects of major essential oils were studied. The analyses conducted by gas chromatography and mass spectroscopy (GC-MS) revealed the essential oils of F. glaberrima. The F. glaberrima essential oil (FGEO) yield was 0.046%, and GC/MS analysis revealed that its major constituents were beta-farnesol (2.96%), l-alpha-terpineol (2.43%), benzenemethanol (2.87%), (Z)-3-hexen-1-ol (5.23%), and 2,6-bis(1,1-dimethylethyl)-4-methylphenol (1.91%). The essential oil had a significant toxic effect against early fourth stage larvae of Aedes aegypti L with an LC(50) value of 28.43 ppm and an LC(90) value of 76.21 ppm. The results could be useful in search for newer, safer, and more effective natural immunotoxicity agents against A. aegypti.</.
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