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Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection

Authors
Cho, EunjungCha, InhyeYoon, KichulYang, Ha NaKim, Hye WonKim, Myung-GyuJo, Sang-KyungCho, Won YongKim, Hyoung Kyu
Issue Date
10월-2010
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
Acute Hepatitis A; Acute Kidney Injury; Lymphohistiocytosis, Hemophagocytic
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.25, no.10, pp.1529 - 1531
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
25
Number
10
Start Page
1529
End Page
1531
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/115634
DOI
10.3346/jkms.2010.25.10.1529
ISSN
1011-8934
Abstract
Hepatitis A virus (HAV) infection is generally a self-limited disease, but the infection in adults can be serious, to be often complicated by acute kidney injury (AKI) and rarely by virus-associated hemophagocytic syndrome (VAHS). Our patient, a 48-yr-old man, was diagnosed with HAV infection complicated by dialysis-dependent AKI. His kidney biopsy showed acute tubulointerstitial nephritis with massive infiltration of activated macrophages and T cells, and he progressively demonstrated features of VAHS. With hemodialysis and steroid treatment, he was successfully recovered.
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