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Depressive mood and quality of life in functional gastrointestinal disorders: differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome

Authors
Lee, Heon-JeongLee, Sun-YoungKim, Jeong HwanSung, In-KyungPark, Hyung SeokJin, Choon JoKang, Seung-GulYoon, HiejinChun, Hoon Jai
Issue Date
Sep-2010
Publisher
ELSEVIER SCIENCE INC
Keywords
Functional gastrointestinal disorder; Functional dyspepsia; Irritable bowel syndrome; Quality of life; Rome III
Citation
GENERAL HOSPITAL PSYCHIATRY, v.32, no.5, pp.499 - 502
Indexed
SCIE
SSCI
AHCI
SCOPUS
Journal Title
GENERAL HOSPITAL PSYCHIATRY
Volume
32
Number
5
Start Page
499
End Page
502
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/115792
DOI
10.1016/j.genhosppsych.2010.05.002
ISSN
0163-8343
Abstract
Objective: To investigate the differences in depressive mood and quality of life in patients with between functional dyspepsia (FD), irritable bowel syndrome (IBS), and FD-IBS overlap as diagnosed based on Rome III criteria. Methods: The subjects completed a questionnaire based on Rome III criteria, the Beck Depressive Inventory (BDI) including Cognitive Depression Index (CDI) for depressive mood evaluation and the 36-item Short Form general health survey (SF-36) for quality of life assessment. Upper gastrointestinal endoscopy and colonoscopy were performed to exclude organic disease. Results: Of 279 subjects, 70 and 124 subjects were diagnosed as FD and IBS, respectively. FD-IBS overlap patients (n=42) and FD alone patients (n=28) showed higher BDI scores than normal subjects (n=127) (P<.001 and P=.02, respectively), whereas that of IBS alone patients (n=82) did not show difference (P=.17). All the SF-36 subscores of the FD-IBS overlap patients were significantly lower than normal subjects (P<.05). Conclusions: Depressive mood was significantly related to FD and FD-IBS overlap but not to IBS based on Rome III criteria. FD-IBS overlap patients have worse quality of life than FD-alone and IBS-alone patients. (C) 2010 Elsevier Inc. All rights reserved.
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