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Clinical features and prognostic relevance of ovarian involvement in non-Hodgkin's lymphoma: A Consortium for Improving Survival of Lymphoma (CISL) report

Authors
Yun, JinaKim, Seok JinWon, Jong HoChoi, Chul WonEom, Hyeon SeokKim, Jin SeokKim, Min KyoungKwak, Jae-YongKim, Won SeogSuh, Cheolwon
Issue Date
9월-2010
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Keywords
Lymphoma; Ovary; Prognosis; Rituximab; Chemotherapy; B-cell; T-cell
Citation
LEUKEMIA RESEARCH, v.34, no.9, pp.1175 - 1179
Indexed
SCIE
SCOPUS
Journal Title
LEUKEMIA RESEARCH
Volume
34
Number
9
Start Page
1175
End Page
1179
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/115813
DOI
10.1016/j.leukres.2010.02.010
ISSN
0145-2126
Abstract
Fourteen patients had primary ovarian lymphoma, while eighteen patients had secondary ovarian involvement. There was no significant difference in survival rates between primary and secondary involvement with diffuse large B-cell lymphoma (DLBCL), the most common subtype. The 5-year overall survivals of primary and secondary involvement with DLBCL were 70.0% and 59.3%, respectively. The localized bilateral ovarian involvement showed poorer survival compared to stage III/IV patients with secondary ovarian involvement. Treatment outcomes of secondary ovarian involvement in non-Hodgkin's lymphoma were comparable to those of primary ovarian involvement, suggesting that ovarian involvement does not necessarily predict a worse prognosis for NHL patients. (C) 2010 Elsevier Ltd. All rights reserved.
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