Effects of Body Composition, Leptin, and Adiponectin on Bone Mineral Density in Prepubertal Girls
DC Field | Value | Language |
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dc.contributor.author | Rhie, Young Jun | - |
dc.contributor.author | Lee, Kee Hyoung | - |
dc.contributor.author | Chung, So Chung | - |
dc.contributor.author | Kim, Ho Seong | - |
dc.contributor.author | Kim, Duk Hee | - |
dc.date.accessioned | 2021-09-08T01:14:37Z | - |
dc.date.available | 2021-09-08T01:14:37Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2010-08 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/115969 | - |
dc.description.abstract | Body weight is positively associated with bone mineral density but the relationship between obesity and bone mineral density is unclear. Leptin and adiponectin are potential independent contributors to bone mineral density. We assessed the correlations of body composition, leptin and adiponectin with bone mineral density, and whether leptin, adiponectin and body composition determine bone mineral density independently in prepubertal girls. Forty-eight prepubertal girls were classified into obese and control groups by body mass index. Serum leptin and adiponectin levels were determined by enzyme immunoassay. Bone mineral density was measured using dual energy radiography absorptiometry and body composition was measured using bioelectrical impedance analysis. Lean and fat mass, and leptin were positively correlated with bone mineral density. Lean mass was a positive independent predictor of femoral and L-spine bone mineral density. Serum leptin was a postivie independent predictor of femoral bone mineral density. Fat mass was a negative independent predictor of femoral bone mineral density. In prepubertal girls, lean mass has a favorable effect on bone mineral density. Fat mass seems not to protect the bone structure against osteoporosis, despite increased mechanical loading. Serum leptin may play a biological role in regulating bone metabolism. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | - |
dc.subject | HEALTHY POSTMENOPAUSAL WOMEN | - |
dc.subject | MAPK SIGNALING PATHWAY | - |
dc.subject | FAT MASS | - |
dc.subject | HUMAN OSTEOBLASTS | - |
dc.subject | ADOLESCENTS | - |
dc.subject | OBESITY | - |
dc.subject | CHILDREN | - |
dc.subject | MEN | - |
dc.subject | DETERMINANTS | - |
dc.subject | PREDICTORS | - |
dc.title | Effects of Body Composition, Leptin, and Adiponectin on Bone Mineral Density in Prepubertal Girls | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Rhie, Young Jun | - |
dc.contributor.affiliatedAuthor | Lee, Kee Hyoung | - |
dc.identifier.doi | 10.3346/jkms.2010.25.8.1187 | - |
dc.identifier.scopusid | 2-s2.0-77956583395 | - |
dc.identifier.wosid | 000280750400013 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, v.25, no.8, pp.1187 - 1190 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.title | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.volume | 25 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1187 | - |
dc.citation.endPage | 1190 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001465307 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | HEALTHY POSTMENOPAUSAL WOMEN | - |
dc.subject.keywordPlus | MAPK SIGNALING PATHWAY | - |
dc.subject.keywordPlus | FAT MASS | - |
dc.subject.keywordPlus | HUMAN OSTEOBLASTS | - |
dc.subject.keywordPlus | ADOLESCENTS | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | MEN | - |
dc.subject.keywordPlus | DETERMINANTS | - |
dc.subject.keywordPlus | PREDICTORS | - |
dc.subject.keywordAuthor | Bone Density | - |
dc.subject.keywordAuthor | Body Composition | - |
dc.subject.keywordAuthor | Leptin | - |
dc.subject.keywordAuthor | Adiponectin | - |
dc.subject.keywordAuthor | Obesity | - |
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