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Microwave-assisted amination of 3-bromo-2-chloropyridine with various substituted aminoethanols
- Issue Date
- 28-Jul-2010
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Keywords
- Microwave-assisted amination; 3-Bromo-2-chloropyridine; Aminoethanol; Pyrido[1,4]oxazine
- Citation
- TETRAHEDRON LETTERS, v.51, no.30, pp.3886 - 3889
- Indexed
- SCIE
SCOPUS
- Journal Title
- TETRAHEDRON LETTERS
- Volume
- 51
- Number
- 30
- Start Page
- 3886
- End Page
- 3889
- ISSN
- 0040-4039
- Abstract
- A simple method for microwave-assisted amination of 3-bromo-2-chloropyridine with various substituted aminoethanols is described. The reaction was carried out under microwave irradiation conditions (at 180 degrees C for 1-2 h) and the result was superior in terms of conversion and yield when compared to that of the corresponding conventional heating conditions. (C) 2010 Elsevier Ltd. All rights reserved.
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