Rigiflex Lithography-Based Nanodot Arrays for Localized Surface Plasmon Resonance Biosensors
- Authors
- Park, Dong Kyu; Kim, Hye In; Kim, Jun Pyo; Park, Je Seob; Lee, Su Yeon; Yang, Seung-Man; Lee, Jeewon; Chung, Chan-Hwa; Sim, Sang Jun; Yoo, Pil J.
- Issue Date
- 4-5월-2010
- Publisher
- AMER CHEMICAL SOC
- Citation
- LANGMUIR, v.26, no.9, pp.6119 - 6126
- Indexed
- SCIE
SCOPUS
- Journal Title
- LANGMUIR
- Volume
- 26
- Number
- 9
- Start Page
- 6119
- End Page
- 6126
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/116455
- DOI
- 10.1021/la100598v
- ISSN
- 0743-7463
- Abstract
- We present a facile and robust means of fabricating metallic nanodot arrays for localized surface plasmon resonance (LSPR) biosensors through the strategic coupling of a polymeric template prepared with rigiflex lithography and a subsequent metallization via electrodeposition. Rigiflex lithography provides the capability to realize large-scale nanosized features as well as process flexibility during contact molding. In addition, the electrodeposition process enables wet-based nanoscale metallization with high pattern fidelity and geometric controllability. Generated metallic nanodot arrays can be used as a general platform for LSPR biosensors via the sequential binding of chemicals and biomolecules. Extinction spectra of the corresponding LSPR signal are measured with UV-vis-NIR spectroscopy, from which the pattern size and shape dependence of LSPR are readily confirmed. The feasibility of a very sensitive biosensor is demonstrated by the targeted binding of human immunoglobulin G, yielding subnanomolar detection capability with high selectivity.
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Collections - College of Engineering > Department of Chemical and Biological Engineering > 1. Journal Articles
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