Effectiveness of Topical Chia Seed Oil on Pruritus of End-stage Renal Disease (ESRD) Patients and Healthy Volunteers
DC Field | Value | Language |
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dc.contributor.author | Jeong, Se Kyoo | - |
dc.contributor.author | Park, Hyun Jung | - |
dc.contributor.author | Park, Byeong Deog | - |
dc.contributor.author | Kim, Il-Hwan | - |
dc.date.accessioned | 2021-09-08T03:31:27Z | - |
dc.date.available | 2021-09-08T03:31:27Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010-05 | - |
dc.identifier.issn | 1013-9087 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/116539 | - |
dc.description.abstract | Background: Several studies have been performed to evaluate the efficacy of dietary n-3 fatty acid for patients with renal dysfunction. While about 40% to 80% of patients with end-stage renal disease (ESRD) complain about pruritus and xerosis, there are few reports on the effects of topical n-3 fatty acid on these symptoms. Objective: In order to investigate the possible beneficial effects of topical n-3 fatty acid, oils extracted from chia (Salvia hispanica) seed were formulated into topical products, the effects of which were measured. Methods: Five healthy volunteers having xerotic pruritus symptoms and 5 patients with pruritus caused by either ESRD or diabetes were involved in this study. A topical formulation containing 4% chia seed oils were applied for an 8-week duration. Subjective itching symptoms were assessed on a 6-point scale, as were other skin functions, namely trans-epidermal water loss and skin capacitance. Results: After the 8 weeks of application, significant improvements in skin hydration, lichen simplex chronicus, and prurigo nodularis were observed in all patients. A similar improvement was also observed among healthy volunteers with xerotic pruritus. Improvement of epidermal permeability barrier function and skin hydration, represented by trans-epidermal water loss and skin capacitance, respectively, were also observed. No adverse effects were observed in all the tested patients and volunteers. Conclusion: Chia seed oil can be used as an adjuvant moisturizing agent for pruritic skin, including that of ESRD patients. (Ann Dermatol 22(2) 143 similar to 148, 2010) | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN DERMATOLOGICAL ASSOC | - |
dc.subject | GAMMA-LINOLENIC ACID | - |
dc.subject | UREMIC PRURITUS | - |
dc.subject | HEMODIALYSIS | - |
dc.title | Effectiveness of Topical Chia Seed Oil on Pruritus of End-stage Renal Disease (ESRD) Patients and Healthy Volunteers | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Il-Hwan | - |
dc.identifier.doi | 10.5021/ad.2010.22.2.143 | - |
dc.identifier.scopusid | 2-s2.0-77954739719 | - |
dc.identifier.wosid | 000279787800003 | - |
dc.identifier.bibliographicCitation | ANNALS OF DERMATOLOGY, v.22, no.2, pp.143 - 148 | - |
dc.relation.isPartOf | ANNALS OF DERMATOLOGY | - |
dc.citation.title | ANNALS OF DERMATOLOGY | - |
dc.citation.volume | 22 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 143 | - |
dc.citation.endPage | 148 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001447945 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.subject.keywordPlus | GAMMA-LINOLENIC ACID | - |
dc.subject.keywordPlus | UREMIC PRURITUS | - |
dc.subject.keywordPlus | HEMODIALYSIS | - |
dc.subject.keywordAuthor | Alpha-linolenic acid | - |
dc.subject.keywordAuthor | Chia seed oil | - |
dc.subject.keywordAuthor | End-stage renal failure | - |
dc.subject.keywordAuthor | Omega-3 fatty acids | - |
dc.subject.keywordAuthor | Pruritus | - |
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