Radiosurgery for brain metastasis from advanced gastric cancer
- Authors
- Han, Jung Ho; Kim, Dong Gyu; Chung, Hyun-Tai; Kim, Chae-Yong; Park, Chul-Kee; Chung, Young Seob; Paek, Sun Ha; Yoo, Moon-Won; Kim, Baek-Hui; Jung, Hee-Won
- Issue Date
- 4월-2010
- Publisher
- SPRINGER WIEN
- Keywords
- Brain metastasis; Advanced gastric carcinoma; Gamma Knife radiosurgery; Whole-brain radiotherapy
- Citation
- ACTA NEUROCHIRURGICA, v.152, no.4, pp.605 - 610
- Indexed
- SCIE
SCOPUS
- Journal Title
- ACTA NEUROCHIRURGICA
- Volume
- 152
- Number
- 4
- Start Page
- 605
- End Page
- 610
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/116706
- DOI
- 10.1007/s00701-009-0554-4
- ISSN
- 0001-6268
- Abstract
- We retrospectively evaluated the survival of patients with brain metastases from advanced gastric cancer (AGC) after radiosurgery (RS). Between 1998 and 2007, a total of 11 patients (median age, 61 years; range, 36-70) were diagnosed with brain metastasis from AGC and treated with RS. Each of five (46%) patients had two brain metastases. The median volume of the 16 lesions was 2.9 cm(3) (range, 0.1-33.8). The median marginal dose prescribed was 20 Gy (range, 10-25) at the 50% isodose line. RS was the primary treatment for brain metastases in six patients. As of February 28, 2008, eight (73%) patients had died, and three (27%) were living with stable disease. The median survival time was 17.0 +/- 3.9 months (95% CI, 9.4-24.6). The median progression-free survival time was 9.0 +/- 2.5 months (95% CI, 4.2-13.8). Patients who did not undergo WBRT died within 8 months, and the other six patients treated with WBRT at various time intervals from the diagnosis of brain metastases survived, with a median survival time of 19.0 +/- 3.4 months (95% CI, 12.4-25.6). Radiosurgery seems to be a good alternative to surgical resection for patients with brain metastases from AGC, when performed in conjunction with WBRT.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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