Overexpression of ethionine resistance gene for maximized production of S-adenosylmethionine in Saccharomyces cerevisiae sake kyokai No. 6
DC Field | Value | Language |
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dc.contributor.author | Lee, Sang-Woo | - |
dc.contributor.author | Park, Bu-Soo | - |
dc.contributor.author | Choi, Eun-Sil | - |
dc.contributor.author | Oh, Min-Kyu | - |
dc.date.accessioned | 2021-09-08T04:47:57Z | - |
dc.date.available | 2021-09-08T04:47:57Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010-03 | - |
dc.identifier.issn | 0256-1115 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/116886 | - |
dc.description.abstract | In our previous work, we developed an auxotrophic mutant of Saccharomyces cerevisiae sake kyokai No. 6 strain for the selection of recombinant DNA. Sake yeast can accumulate high amount of S-adenosylmethionine (SAM) that is effective for treating depression, Alzheimer's disease and so on. In this work, we further introduced SAM2 gene and ERC1, a frame-shift mutant of YHR032w, to maximize the production of S-adenosylmethionine in S. cerevisiae sake K6. The recombinant strain accumulated SAM about half of its dry cell weight. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN INSTITUTE CHEMICAL ENGINEERS | - |
dc.subject | ADENOSYL-L-METHIONINE | - |
dc.subject | YEAST | - |
dc.subject | PROTEIN | - |
dc.subject | METHYLATION | - |
dc.subject | EXPRESSION | - |
dc.title | Overexpression of ethionine resistance gene for maximized production of S-adenosylmethionine in Saccharomyces cerevisiae sake kyokai No. 6 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Oh, Min-Kyu | - |
dc.identifier.doi | 10.1007/s11814-010-0100-3 | - |
dc.identifier.scopusid | 2-s2.0-77951640334 | - |
dc.identifier.wosid | 000275218200032 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF CHEMICAL ENGINEERING, v.27, no.2, pp.587 - 589 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF CHEMICAL ENGINEERING | - |
dc.citation.title | KOREAN JOURNAL OF CHEMICAL ENGINEERING | - |
dc.citation.volume | 27 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 587 | - |
dc.citation.endPage | 589 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001423479 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Engineering, Chemical | - |
dc.subject.keywordPlus | ADENOSYL-L-METHIONINE | - |
dc.subject.keywordPlus | YEAST | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | METHYLATION | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordAuthor | S-adenosyl-L-methionine | - |
dc.subject.keywordAuthor | Saccharomyces cerevisiae sake | - |
dc.subject.keywordAuthor | Metabolic Engineering | - |
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